The neonatal heart possesses the ability to proliferate and the capacity to regenerate after
injury; however, the mechanisms underlying these processes are not fully understood …

Background Melatonin is a neurohormone secreted predominantly by the pineal gland that
is demonstrated to be associated with the pathogenesis of multiple sclerosis (MS). This …

Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …

Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Rheumatoid arthritis (RA) is an inflammatory joint disorder characterized by synovial
proliferation and inflammation, with eventual joint destruction if inadequately treated …

This short review aimed at (i) providing an update on the health benefits associated with
melatonin supplementation, while (ii) considering future potential research directions …

Osteoarthritis (OA) is a common chronic degenerative disease of articular cartilage in middle-
aged and older individuals, which can result in the joint pain and dysfunction, and even …

Background Melatonin has been related to the pathophysiology of multiple sclerosis (MS),
and its anti-inflammatory and immunomodulatory properties have been proved in numerous …

In mammals, amino acid metabolism has evolved to act as a critical regulator of innate and
adaptive immune responses. Rheumatoid arthritis (RA) is the most common form of …

Melatonin (MLT) was reported to have therapeutic effects on inflammatory bowel disease
(IBD) such as ulcerative colitis (UC) and Crohn's disease (CD) due to its anti-inflammatory …