Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-
malignant diseases. This is consistent with numerous findings about differentiation …

Skeletal muscle development and regeneration is governed by the combined action of Myf5,
MyoD, Mrf4 and MyoG, also known as the myogenic regulatory factors (MRFs). These …

A recent study conducted the first genome-wide scan for selection in Inuit from Greenland
using single nucleotide polymorphism chip data. Here, we report that selection in the region …

5hmC is generally enriched about 0.5–2 kb upstream and downstream of the transcription
start site (TSS) but is depleted closer to the TSS at moderately or highly transcribed genes …

ABSTRACT DNA methylation can affect tissue-specific gene transcription in ways that are
difficult to discern from studies focused on genome-wide analyses of differentially …

Simple Summary Folic acid (FA) participates in DNA synthesis and in DNA methylation;
hence, it has a dual role in established neoplasms. We aimed to observe this phenomenon …

TBX15, which encodes a differentiation-related transcription factor, displays promoter-
adjacent DNA hypermethylation in myoblasts and skeletal muscle (psoas) that is absent …

TEAD4 is a transcription factor that plays a crucial role in the Hippo pathway by regulating
the expression of genes related to proliferation and apoptosis. It is also involved in the …

DNA methylation is an important epigenetic modification that contributes to the lineage
commitment and specific functions of different cell types. In this study, we compared …

Osteoporosis is a serious public health issue, which is mostly characterized by low bone
mineral density (BMD). To search for additional genetic susceptibility loci underlying BMD …