Guidelines on the use of therapeutic apheresis in clinical practice—evidence‐based approach from the Writing Committee of the American Society for Apheresis: the …
The American Society for Apheresis (ASFA) JCA Special Issue Writing Committee is
charged with reviewing, updating and categorizating indications for therapeutic apheresis …
charged with reviewing, updating and categorizating indications for therapeutic apheresis …
Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype
M Noris, J Caprioli, E Bresin, C Mossali… - Clinical Journal of the …, 2010 - journals.lww.com
Background and objectives: Hemolytic uremic syndrome (HUS) is characterized by
microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. Most …
microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. Most …
[HTML][HTML] Terminal complement inhibitor eculizumab in adult patients with atypical hemolytic uremic syndrome: a single-arm, open-label trial
F Fakhouri, M Hourmant, JM Campistol… - American journal of …, 2016 - Elsevier
Background Atypical hemolytic uremic syndrome (aHUS) is a rare genetic life-threatening
disease of chronic uncontrolled complement activation leading to thrombotic …
disease of chronic uncontrolled complement activation leading to thrombotic …
Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group
Pregnancy and postpartum are high-risk periods for different forms of thrombotic
microangiopathy (TMA). However, the management of pregnancy-associated TMA remains …
microangiopathy (TMA). However, the management of pregnancy-associated TMA remains …
Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice
N Knoers, C Antignac, C Bergmann… - Nephrology Dialysis …, 2022 - academic.oup.com
The overall diagnostic yield of massively parallel sequencing–based tests in patients with
chronic kidney disease (CKD) is 30% for paediatric cases and 6–30% for adult cases. These …
chronic kidney disease (CKD) is 30% for paediatric cases and 6–30% for adult cases. These …
Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome
Pathologic thrombosis is a major cause of mortality. Hemolytic-uremic syndrome (HUS)
features episodes of small-vessel thrombosis resulting in microangiopathic hemolytic …
features episodes of small-vessel thrombosis resulting in microangiopathic hemolytic …
[HTML][HTML] Membranoproliferative glomerulonephritis—a new look at an old entity
S Sethi, FC Fervenza - New England Journal of Medicine, 2012 - Mass Medical Soc
This review discusses the causes, pathogenesis, and clinical management of
membranoproliferative glomerulonephritis, which accounts for 7 to 10% of biopsy-confirmed …
membranoproliferative glomerulonephritis, which accounts for 7 to 10% of biopsy-confirmed …
[HTML][HTML] Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome
LA Greenbaum, M Fila, G Ardissino, SI Al-Akash… - Kidney international, 2016 - Elsevier
Atypical hemolytic uremic syndrome (aHUS) is caused by alternative complement pathway
dysregulation, leading to systemic thrombotic microangiopathy (TMA) and severe end-organ …
dysregulation, leading to systemic thrombotic microangiopathy (TMA) and severe end-organ …
[HTML][HTML] Heme on innate immunity and inflammation
Heme is an essential molecule expressed ubiquitously all through our tissues. Heme plays
major functions in cellular physiology and metabolism as the prosthetic group of diverse …
major functions in cellular physiology and metabolism as the prosthetic group of diverse …
A new paradigm: diagnosis and management of HSCT-associated thrombotic microangiopathy as multi-system endothelial injury
Hematopoietic stem cell transplantation (HSCT)-associated thrombotic microangiopathy (TA-
TMA) is now a well-recognized and potentially severe complication of HSCT that carries a …
TMA) is now a well-recognized and potentially severe complication of HSCT that carries a …