Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

The search for a connection between diet and human cancer has a long history in cancer
research, as has interest in the mechanisms by which dietary factors might increase or …

Genome-wide analysis of DNA methylation has now become a relatively inexpensive
technique thanks to array-based methylation profiling technologies. The recently developed …

To clarify the mechanisms of diseases, such as cancer, studies analyzing genetic mutations
have been actively conducted for a long time, and a large number of achievements have …

Liquid biopsy based on cell-free DNA (cfDNA) enables non-invasive dynamic assessment of
disease status in patients with cancer, both in the early and advanced settings. The analysis …

An important feature of cancer development and progression is the change in DNA
methylation patterns, characterized by the hypermethylation of specific genes concurrently …

Background The newly released 450k DNA methylation array from Illumina, Inc. offers the
possibility to analyze more than 480,000 individual CpG sites in a user friendly standardized …

Abstract Background Infinium HumanMethylation 450 BeadChip Arrays by Illumina (Illumina
HM450K) are among the most popular CpG microarray platforms widely used in biological …

Sight threatening immune responses that damage the eye characterize intraocular
inflammatory diseases. These diseases including uveitis and age-related macular …

Diffuse large B-cell lymphoma (DLBCL) is the most common canine aggressive B-cell
lymphoma worldwide, and new recent molecular approaches have shown that DLBCL …