[HTML][HTML] DNA methylation biomarkers: cancer and beyond
Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …
or disease can be identified or monitored. They can reflect past environmental exposures …
[HTML][HTML] Diet, nutrition, and cancer epigenetics
C Sapienza, JP Issa - Annual review of nutrition, 2016 - annualreviews.org
The search for a connection between diet and human cancer has a long history in cancer
research, as has interest in the mechanisms by which dietary factors might increase or …
research, as has interest in the mechanisms by which dietary factors might increase or …
[HTML][HTML] Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip
Genome-wide analysis of DNA methylation has now become a relatively inexpensive
technique thanks to array-based methylation profiling technologies. The recently developed …
technique thanks to array-based methylation profiling technologies. The recently developed …
[HTML][HTML] Epigenetics analysis and integrated analysis of multiomics data, including epigenetic data, using artificial intelligence in the era of precision medicine
To clarify the mechanisms of diseases, such as cancer, studies analyzing genetic mutations
have been actively conducted for a long time, and a large number of achievements have …
have been actively conducted for a long time, and a large number of achievements have …
[HTML][HTML] Cell-free DNA-methylation-based methods and applications in oncology
F Galardi, F De Luca, D Romagnoli, C Biagioni… - Biomolecules, 2020 - mdpi.com
Liquid biopsy based on cell-free DNA (cfDNA) enables non-invasive dynamic assessment of
disease status in patients with cancer, both in the early and advanced settings. The analysis …
disease status in patients with cancer, both in the early and advanced settings. The analysis …
Hypomethylation of repeated DNA sequences in cancer
An important feature of cancer development and progression is the change in DNA
methylation patterns, characterized by the hypermethylation of specific genes concurrently …
methylation patterns, characterized by the hypermethylation of specific genes concurrently …
[HTML][HTML] Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc.
J Roessler, O Ammerpohl, J Gutwein, B Hasemeier… - BMC research …, 2012 - Springer
Background The newly released 450k DNA methylation array from Illumina, Inc. offers the
possibility to analyze more than 480,000 individual CpG sites in a user friendly standardized …
possibility to analyze more than 480,000 individual CpG sites in a user friendly standardized …
[HTML][HTML] Impact of SNPs on methylation readouts by Illumina Infinium HumanMethylation450 BeadChip Array: implications for comparative population studies
P Daca-Roszak, A Pfeifer, J Żebracka-Gala, D Rusinek… - BMC genomics, 2015 - Springer
Abstract Background Infinium HumanMethylation 450 BeadChip Arrays by Illumina (Illumina
HM450K) are among the most popular CpG microarray platforms widely used in biological …
HM450K) are among the most popular CpG microarray platforms widely used in biological …
[HTML][HTML] Epigenetics, microbiota, and intraocular inflammation: New paradigms of immune regulation in the eye
X Wen, X Hu, L Miao, X Ge, Y Deng, PW Bible… - Progress in Retinal and …, 2018 - Elsevier
Sight threatening immune responses that damage the eye characterize intraocular
inflammatory diseases. These diseases including uveitis and age-related macular …
inflammatory diseases. These diseases including uveitis and age-related macular …
Introduction to epigenetics
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …