DNA methylation: shared and divergent features across eukaryotes

RJ Schmitz, ZA Lewis, MG Goll - Trends in Genetics, 2019 - cell.com
Chemical modification of nucleotide bases in DNA provides one mechanism for conveying
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …

Small RNA-mediated DNA methylation during plant reproduction

HT Chow, RA Mosher - The Plant Cell, 2023 - academic.oup.com
Reproductive tissues are a rich source of small RNAs, including several classes of short
interfering (si) RNAs that are restricted to this stage of development. In addition to RNA …

DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development

L He, H Huang, M Bradai, C Zhao, Y You, J Ma… - Nature …, 2022 - nature.com
A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …

Population-level analysis reveals the widespread occurrence and phenotypic consequence of DNA methylation variation not tagged by genetic variation in maize

J Xu, G Chen, PJ Hermanson, Q Xu, C Sun, W Chen… - Genome biology, 2019 - Springer
Background DNA methylation can provide a source of heritable information that is
sometimes entirely uncoupled from genetic variation. However, the extent of this uncoupling …

Evolutionary and functional genomics of DNA methylation in maize domestication and improvement

G Xu, J Lyu, Q Li, H Liu, D Wang, M Zhang… - Nature …, 2020 - nature.com
DNA methylation is a ubiquitous chromatin feature, present in 25% of cytosines in the maize
genome, but variation and evolution of the methylation landscape during maize …

Exploring impact of recombination landscapes on breeding outcomes

R Epstein, N Sajai, M Zelkowski… - Proceedings of the …, 2023 - National Acad Sciences
Plant breeding relies on crossing-over to create novel combinations of alleles needed to
confer increased productivity and other desired traits in new varieties. However, crossover …

The maize gene maternal derepression of r1 encodes a DNA glycosylase that demethylates DNA and reduces siRNA expression in the endosperm

JI Gent, KM Higgins, KW Swentowsky, FF Fu… - The Plant …, 2022 - academic.oup.com
Demethylation of transposons can activate the expression of nearby genes and cause
imprinted gene expression in the endosperm; this demethylation is hypothesized to lead to …

Pathway conversion enables a double-lock mechanism to maintain DNA methylation and genome stability

L He, C Zhao, Q Zhang, G Zinta… - Proceedings of the …, 2021 - National Acad Sciences
The CMT2 and RNA-directed DNA methylation (RdDM) pathways have been proposed to
separately maintain CHH methylation in specific regions of the Arabidopsis thaliana …

The evolutionary volte-face of transposable elements: from harmful jumping genes to major drivers of genetic innovation

M Nicolau, N Picault, G Moissiard - Cells, 2021 - mdpi.com
Transposable elements (TEs) are self-replicating DNA elements that constitute major
fractions of eukaryote genomes. Their ability to transpose can modify the genome structure …

RNA m6A modification facilitates DNA methylation during maize kernel development

JH Luo, T Guo, M Wang, JH Liu, LM Zheng… - Plant …, 2024 - academic.oup.com
Abstract N6-methyladenosine (m6A) in mRNA and 5-methylcytosine (5mC) in DNA have
critical functions for regulating gene expression and modulating plant growth and …