[HTML][HTML] Mesenchymal stem cell therapy for doxorubicin-induced cardiomyopathy: potential mechanisms, governing factors, and implications of the heart stem cell …
Over the past decades, researchers have reported several mechanisms for doxorubicin
(DOX)-induced cardiomyopathy, including oxidative stress, inflammation, and apoptosis …
(DOX)-induced cardiomyopathy, including oxidative stress, inflammation, and apoptosis …
The mesenchymoangioblast, mesodermal precursor for mesenchymal and endothelial cells
II Slukvin, A Kumar - Cellular and molecular life sciences, 2018 - Springer
Mesenchymoangioblast (MB) is the earliest precursor for endothelial and mesenchymal
cells originating from APLNR+ PDGFRα+ KDR+ mesoderm in human pluripotent stem cell …
cells originating from APLNR+ PDGFRα+ KDR+ mesoderm in human pluripotent stem cell …
[HTML][HTML] Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder
A Kim, HY Yu, J Heo, M Song, JH Shin, J Lim… - Scientific reports, 2016 - nature.com
Abuse of the hallucinogenic drug ketamine promotes the development of lower urinary tract
symptoms that resemble interstitial cystitis. The pathophysiology of ketamine-induced cystitis …
symptoms that resemble interstitial cystitis. The pathophysiology of ketamine-induced cystitis …
[HTML][HTML] The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity
The anthracycline doxorubicin (Dox) is widely used in oncology, but it may cause a
cardiomyopathy with bleak prognosis that cannot be effectively prevented. The secretome of …
cardiomyopathy with bleak prognosis that cannot be effectively prevented. The secretome of …
[HTML][HTML] Bone marrow mesenchymal stromal cell-derived small extracellular vesicles: A novel therapeutic agent in ischemic heart diseases
W Chang, P Li - Frontiers in Pharmacology, 2023 - frontiersin.org
Myocardial injury is a major pathological factor that causes death in patients with heart
diseases. In recent years, mesenchymal stromal cells (MSCs) have been generally used in …
diseases. In recent years, mesenchymal stromal cells (MSCs) have been generally used in …
Anti-fibrotic mechanisms of exogenously-expanded mesenchymal stromal cells for fibrotic diseases
JS Rockel, R Rabani, S Viswanathan - Seminars in cell & developmental …, 2020 - Elsevier
Most chronic diseases involving inflammation have a fibrotic component that involves
remodeling and excess accumulation of extracellular matrix components. Left unchecked …
remodeling and excess accumulation of extracellular matrix components. Left unchecked …
Haemin pre‐treatment augments the cardiac protection of mesenchymal stem cells by inhibiting mitochondrial fission and improving survival
R Deng, Y Liu, H He, H Zhang, C Zhao… - Journal of Cellular …, 2020 - Wiley Online Library
The cardiac protection of mesenchymal stem cell (MSC) transplantation for myocardial
infarction (MI) is largely hampered by low cell survival. Haem oxygenase 1 (HO‐1) plays a …
infarction (MI) is largely hampered by low cell survival. Haem oxygenase 1 (HO‐1) plays a …
Brain‐derived neurotrophic factor attenuates doxorubicin‐induced cardiac dysfunction through activating Akt signalling in rats
P Hang, J Zhao, L Sun, M Li, Y Han… - Journal of Cellular and …, 2017 - Wiley Online Library
The clinical application of doxorubicin (Dox) is limited by its adverse effect of cardiotoxicity.
Previous studies have suggested the cardioprotective effect of brain‐derived neurotrophic …
Previous studies have suggested the cardioprotective effect of brain‐derived neurotrophic …
[HTML][HTML] Macrophage migration inhibitory factor rescues mesenchymal stem cells from doxorubicin-induced senescence though the PI3K-Akt signaling pathway
W Xia, M Hou - International journal of molecular …, 2018 - spandidos-publications.com
Doxorubicin (DOXO), an anthracycline antibiotic, is a commonly used anticancer drug.
Despite its widespread usage, the therapeutic effects of DOXO are limited by its …
Despite its widespread usage, the therapeutic effects of DOXO are limited by its …
[HTML][HTML] Adipose-derived mesenchymal stem cells isolated from patients with abdominal aortic aneurysm exhibit senescence phenomena
X Huang, H Zhang, X Liang, Y Hong, M Mao… - … Medicine and Cellular …, 2019 - hindawi.com
Mesenchymal stem cells (MSCs) have shown beneficial effects in the treatment of
abdominal aortic aneurysm (AAA). Nonetheless, the biological properties of adipose-derived …
abdominal aortic aneurysm (AAA). Nonetheless, the biological properties of adipose-derived …