[HTML][HTML] Lessons learned from failures and success stories of HIV breakthroughs: are we getting closer to an HIV cure?

V Kalidasan, K Theva Das - Frontiers in Microbiology, 2020 - frontiersin.org
There is a continuous search for an HIV cure as the success of ART in blocking HIV
replication and the role of CD4+ T cells in HIV pathogenesis and immunity do not entirely …

Toward precise CRISPR DNA fragment editing and predictable 3D genome engineering

Q Wu, J Shou - Journal of Molecular Cell Biology, 2020 - academic.oup.com
Ever since gene targeting or specific modification of genome sequences in mice was
achieved in the early 1980s, the reverse genetic approach of precise editing of any genomic …

Heritable genome editing and the downsides of a global moratorium

KL Macintosh - The CRISPR Journal, 2019 - liebertpub.com
Abstract In 2018, Dr. He Jiankui reported that he had edited human embryos and transferred
them to a woman, causing her to give birth to twin girls with modified genomes. An …

Live very long and prosper? Transhumanist visions and ambitions in 2021 and beyond…

J Takhar, HR Houston, N Dholakia - Journal of Marketing …, 2022 - Taylor & Francis
In 2005 the lead guest editor of this special issue came upon a book by Ray Kurzweil and
Terry Grossman entitled Fantastic Voyage: Live Long Enough to Live Forever. The title …

Reexamining the ethics of human germline editing in the wake of scandal

KM Meagher, MA Allyse, Z Master, RR Sharp - Mayo Clinic Proceedings, 2020 - Elsevier
In November 2018, the announcement that genetically edited human embryos had been
used for reproductive purposes caused international uproar; many observers argued that …

[HTML][HTML] Is Malaysia ready for human gene editing: A regulatory, biosafety and biosecurity perspective

V Kalidasan, K Theva Das - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Gene editing platforms have revolutionized the field of genetics with a direct impact on the
public health system. Although there are apparent benefits, it is often accompanied by public …

Designer babies?!” A CRISPR‐based learning module for undergraduates built around the CCR5 gene

JN Pieczynski, HL Kee - Biochemistry and Molecular Biology …, 2021 - Wiley Online Library
CRISPR‐cas technology is being incorporated into undergraduate biology curriculum
through lab experiences to immerse students in modern technology that is rapidly changing …

The hidden cost of genetic resistance to HIV-1

J Luban - Nature medicine, 2019 - nature.com
The hidden cost of genetic resistance to HIV-1 | Nature Medicine Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Introduction: Live very long and prosper? Transhumanist visions and ambitions in 2021 and beyond…

J Takhar, R Houston, N Dholakia - … and Biotechnologies in …, 2022 - taylorfrancis.com
Transhumanists are keen on altering and improving the human body;'transhumanists
typically want to choose its form and be able to inhabit different bodies, including virtual …

Liver targeted gene therapy: Insights into emerging therapies

CG Moscoso, CJ Steer - Drug Discovery Today: Technologies, 2019 - Elsevier
The large number of monogenic metabolic disorders originating in the liver poses a unique
opportunity for development of gene therapy modalities to pursue curative approaches …