[HTML][HTML] Advances in the early diagnosis of hepatocellular carcinoma

W Wang, C Wei - Genes & diseases, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers globally. In contrast to
the declining death rates observed for all other common cancers such as breast, lung, and …

[HTML][HTML] Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential

KT Jurdziński, J Potempa, AM Grabiec - Clinical epigenetics, 2020 - Springer
Epigenetic mechanisms, namely DNA and histone modifications, are critical regulators of
immunity and inflammation which have emerged as potential targets for immunomodulating …

DNA methylation-based variation between human populations

F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …

DNA methylation and application in forensic sciences

F Kader, M Ghai - Forensic science international, 2015 - Elsevier
DNA methylation of cytosine residues is a stable epigenetic alteration, beginning as early as
foetal development in the uterus and continuously evolving throughout life. DNA methylation …

Epigenetic alterations of chromosome 3 revealed by NotI‐microarrays in clear cell renal cell carcinoma

AA Dmitriev, EE Rudenko… - BioMed research …, 2014 - Wiley Online Library
This study aimed to clarify epigenetic and genetic alterations that occur during renal
carcinogenesis. The original method includes chromosome 3 specific NotI‐microarrays …

Liquid biopsies for hepatocellular carcinoma

YH Su, AK Kim, S Jain - Translational Research, 2018 - Elsevier
Hepatocellular carcinoma (HCC) is the world's second leading cause of cancer death;
82.4% of patients die within 5 years. This grim prognosis is the consequence of a lack of …

HPV33 DNA methylation measurement improves cervical pre-cancer risk estimation of an HPV16, HPV18, HPV31 and\textit {EPB41L3} methylation classifier

AR Brentnall, N Vasiljevic… - Cancer …, 2015 - content.iospress.com
BACKGROUND: Persistent infection% by with high risk human papillomavirus (hrHPV) types
causes cervical cancer but most women who test positive are at very low risk of neoplasia …

A DNA methylation classifier of cervical precancer based on human papillomavirus and human genes

AR Brentnall, N Vasiljević… - … journal of cancer, 2014 - Wiley Online Library
Testing for high‐risk (hr) types of human papillomavirus (HPV) is highly sensitive as a
screening test of high‐grade cervical intraepithelial neoplastic (CIN2/3) disease, the …

Methylation of FBN1, SPG20, ITF2, RUNX3, SNCA, MLH1, and SEPT9 genes in circulating cell-free DNA as biomarkers of colorectal cancer

M Alizadeh-Sedigh, MS Fazeli… - Cancer …, 2022 - content.iospress.com
BACKGROUND: Investigating aberrant tumor-specific methylation in plasma cell-free DNA
provides a promising and noninvasive biomarker for cancer detection. OBJECTIVE: We …

[HTML][HTML] Development and evaluation of novel statistical methods in urine biomarker-based hepatocellular carcinoma screening

J Wang, S Jain, D Chen, W Song, CT Hu, YH Su - Scientific reports, 2018 - nature.com
Hepatocellular carcinoma is one of the fastest growing cancers in the US and has a low
survival rate, partly due to difficulties in early detection. Because of HCC's high …