Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Abstract Rationale: Breast cancer (BrCa) is the most common cancer worldwide, and the 5-
year relative survival rate has declined in patients diagnosed at stage IV. Advanced BrCa is …

Epigenetic modifications are heritable changes in gene expression not encoded by the DNA
sequence. In the past decade, great strides have been made in characterizing epigenetic …

Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in
the mammalian genome and is essential for embryonic viability. With several of the key …

An altered pattern of epigenetic modifications is central to many common human diseases,
including cancer. Many studies have explored the mosaic patterns of DNA methylation and …

Understanding the cellular and molecular mechanisms underlying the formation and
maintenance of memories is a central goal of the neuroscience community. It is well …

DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …

Human immunodeficiency virus type 1 (HIV-1) persists in a latent state within resting CD4+ T
cells of infected persons treated with highly active antiretroviral therapy (HAART). This …

Methylation of DNA and lysine 9 of histone H3 (H3K9) are well‐conserved epigenetic marks
for transcriptional silencing. Although H3K9 methylation directs DNA methylation in …