COVID-19 associated with cryptococcosis: a new challenge during the pandemic

KS Chan, CC Lai, WL Yu, CM Chao - Journal of Fungi, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a great threat to global health. In addition to SARS-CoV-2 …

Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections

KD Goughenour, AS Nair, J Xu, MA Olszewski… - Journal of Fungi, 2023 - mdpi.com
Fungal infections are an increasingly growing public health concern, and Cryptococcus is
one of the most problematic fungal organisms causing substantial mortality and morbidity …

Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis

S Cohen-Kedar, E Shaham Barda… - Frontiers in …, 2023 - frontiersin.org
Background Intestinal epithelial cells (IECs) are the first to encounter luminal
microorganisms and actively participate in intestinal immunity. We reported that IECs …

Dectin‐3‐targeted antifungal liposomes efficiently bind and kill diverse fungal pathogens

QJ Choudhury, S Ambati, CD Link, X Lin… - Molecular …, 2023 - Wiley Online Library
DectiSomes are anti‐infective drug‐loaded liposomes targeted to pathogenic cells by
pathogen receptors including the Dectins. We have previously used C‐type lectin (CTL) …

Lignosulfonate rapidly inactivates human immunodeficiency and herpes simplex viruses

K Fukuchi, T Koshikawa, D Asai, M Inomata… - Medicines, 2021 - mdpi.com
Background: Very few studies of the antiviral potential of lignosulfonates have been
published. With the aim of oral application, among various groups of natural products, the …

Role of CARD9 in cell-and organ-specific immune responses in various infections

JS Lee, C Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
The caspase recruitment domain-containing protein 9 (CARD9) is an intracellular adaptor
protein that is abundantly expressed in cells of the myeloid lineage, such as neutrophils …

PAMPs and host immune response in cryptococcal infection

K Sato, K Kawakami - Medical Mycology Journal, 2022 - jstage.jst.go.jp
Cryptococcus spp. are yeast-type opportunistic fungal pathogens with thick polysaccharide
capsules that infect the lungs via airborne routes and frequently cause fatal …

Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus Species

BN Conn, KL Wozniak - Journal of Fungi, 2023 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes over 180,000
annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells …

High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2

L Almeida, R van Roey, TA Patente, F Otto… - Frontiers in …, 2024 - frontiersin.org
The parasitic helminth Schistosoma mansoni is a potent inducer of type 2 immune
responses by stimulating dendritic cells (DCs) to prime T helper 2 (Th2) responses. We …

Innate phase production of IFN-γ by memory and effector T cells expressing early activation marker CD69 during infection with Cryptococcus deneoformans in the …

A Miyahara, A Umeki, K Sato, T Nomura… - Infection and …, 2024 - Am Soc Microbiol
Cryptococcus deneoformans is a yeast-type fungus that causes fatal meningoencephalitis in
immunocompromised patients and evades phagocytic cell elimination through an escape …