Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

The alarming increase in the prevalence of metabolic pathologies is of worldwide concern
and has been linked not only to genetic factors but also to a large number of non-genetic …

Developmental programming, which proposes that “insults” or “stressors” during intrauterine
or postnatal development can have not only immediate but also long-term consequences for …

Background Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina
Infinium Methylation bead arrays is often used to explore the connections between in utero …

The maternal diet is critically important before and during pregnancy for the optimum
development of the fetus [1]. The prenatal environment, such as maternal and environmental …

Background: It is still unelucidated how hormonal alterations affect developing organisms
and their descendants. Particularly, the effects of androgen levels are of clinical relevance …

Background Chronic preconception paternal alcohol use adversely modifies the sperm
epigenome, inducing fetoplacental and craniofacial growth defects in the offspring of …

In recent years, there has been a growing interest in identifying subcellular causes of male
infertility, and sperm DNA fragmentation (SDF) research has been at the forefront of this …

Paternal alcohol use is emerging as a plausible driver of alcohol-related growth and
patterning defects. Studies from our lab using an inbred C57Bl/6 J mouse model suggest …

Seminal fluid, once believed to be sterile, is now recognized as constituting a complex and
dynamic environment inhabited by a diverse community of microorganisms. However …