Generation of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency
T Ito, Y Sendai, S Yamazaki, M Seki-Soma, K Hirose… - PloS one, 2014 - journals.plos.org
Although severe combined immune deficiency (SCID) is a very important research model for
mice and SCID mice are widely used, there are only few reports describing the SCID pig …
mice and SCID mice are widely used, there are only few reports describing the SCID pig …
Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells
Many CpG islands have tissue-dependent and differentially methylated regions (T-DMRs) in
normal cells and tissues. To elucidate how DNA methyltransferases (Dnmts) participate in …
normal cells and tissues. To elucidate how DNA methyltransferases (Dnmts) participate in …
[HTML][HTML] Aging of common carp (Cyprinus carpio L.) sperm induced by short-term storage does not alter global DNA methylation and specific histone modifications in …
Short-term storage of sperm is a useful tool to synchronize the availability of male and
female gametes for fertilization in a hatchery. Induced aging by short-term storage has been …
female gametes for fertilization in a hatchery. Induced aging by short-term storage has been …
Neonatal exposure to diethylstilbestrol alters the expression of DNA methyltransferases and methylation of genomic DNA in the epididymis of mice
K Sato, H Fukata, Y Kogo, J Ohgane, K Shiota… - Endocrine …, 2006 - jstage.jst.go.jp
Fetal and neonatal exposure to diethylstilbestrol (DES) is known to cause many
abnormalities, such as cancer, in the male and female reproductive tracts later in life, and …
abnormalities, such as cancer, in the male and female reproductive tracts later in life, and …
Tissue-specific expression of estrogen receptor 1 is regulated by DNA methylation in a T-DMR
R Maekawa, S Sato, M Okada, L Lee… - Molecular …, 2016 - academic.oup.com
The mechanism controlling tissue-specific expression of estrogen receptor 1 (ESR1) is
unclear. In other genes, DNA methylation of a region called the tissue-dependent and …
unclear. In other genes, DNA methylation of a region called the tissue-dependent and …
Genome-wide analysis of DNA methylation status of CpG islands in embryoid bodies, teratomas, and fetuses
Differentiation of embryonic stem (ES) cells into embryoid bodies (EBs) provides an in vitro
system for the study of early lineage determination during mammalian development. We …
system for the study of early lineage determination during mammalian development. We …
Effect of histone acetylation modification with sodium butyrate, a histone deacetylase inhibitor, on cell cycle, apoptosis, ploidy and gene expression in porcine fetal …
BM Kumar, HJ Song, SK Cho… - … of Reproduction and …, 2007 - jstage.jst.go.jp
The present study evaluated the effective dose of sodium butyrate (NaB), a histone
deacetylase (HDAC) inhibitor, for determination of the level of enhancement of histone …
deacetylase (HDAC) inhibitor, for determination of the level of enhancement of histone …
Disease-dependent differently methylated regions (D-DMRs) of DNA are enriched on the X chromosome in uterine leiomyoma
R Maekawa, S Yagi, J Ohgane, Y Yamagata… - … of Reproduction and …, 2011 - jstage.jst.go.jp
Uterine leiomyoma is the most common benign tumor in women. Although responsible gene
mutations have not been found in leiomyomas, they represent a progressive disease with …
mutations have not been found in leiomyomas, they represent a progressive disease with …
Differential differences in methylation status of putative imprinted genes among cloned swine genomes
CJ Shen, WTK Cheng, SC Wu, HL Chen, TC Tsai… - PLoS …, 2012 - journals.plos.org
DNA methylation is a major epigenetic modification in the mammalian genome that
regulates crucial aspects of gene function. Mammalian cloning by somatic cell nuclear …
regulates crucial aspects of gene function. Mammalian cloning by somatic cell nuclear …
Erasure of methylation imprint at the promoter and CTCF-binding site upstream of H19 in human testicular germ cell tumors of adolescents indicate their fetal germ cell …
T Kawakami, C Zhang, Y Okada, K Okamoto - Oncogene, 2006 - nature.com
Genome-wide epigenetic modification plays a crucial role in regulating genome functions at
critical stages of development. In particular, DNA methylation is known to be reprogrammed …
critical stages of development. In particular, DNA methylation is known to be reprogrammed …