Variability of physiological brain perfusion in healthy subjects–A systematic review of modifiers. Considerations for multi-center ASL studies

P Clement, HJ Mutsaerts, L Václavů… - Journal of Cerebral …, 2018 - journals.sagepub.com
Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

[HTML][HTML] The human brain in a high altitude natural environment: A review

X Zhang, J Zhang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
With the advancement of in vivo magnetic resonance imaging (MRI) technique, more
detailed information about the human brain at high altitude (HA) has been revealed. The …

Investigations of hypoxia‐induced deoxyhemoglobin as a contrast agent for cerebral perfusion imaging

ES Sayin, J Schulman, J Poublanc… - Human Brain …, 2023 - Wiley Online Library
The assessment of resting perfusion measures (mean transit time, cerebral blood flow, and
cerebral blood volume) with magnetic resonance imaging currently requires the presence of …

Cerebral perfusion using ASL in patients with COVID-19 and neurological manifestations: a retrospective multicenter observational study

FD Ardellier, S Baloglu, M Sokolska, V Noblet… - Journal of …, 2023 - Elsevier
Background and purpose Cerebral hypoperfusion has been reported in patients with COVID-
19 and neurological manifestations in small cohorts. We aimed to systematically assess …

Unexpected reductions in regional cerebral perfusion during prolonged hypoxia

JS Lawley, JH Macdonald, SJ Oliver… - The Journal of …, 2017 - Wiley Online Library
Key points Cognitive performance is impaired by hypoxia despite global cerebral oxygen
delivery and metabolism being maintained. Using arterial spin labelled (ASL) magnetic …

[HTML][HTML] Alteration of functional connectivity despite preserved cerebral oxygenation during acute hypoxia

ME Bakker, I Djerourou, S Belanger, F Lesage… - Scientific Reports, 2023 - nature.com
Resting state networks (RSN), which show the connectivity in the brain in the absence of any
stimuli, are increasingly important to assess brain function. Here, we investigate the changes …

Assessing perfusion in steno-occlusive cerebrovascular disease using transient hypoxia-induced deoxyhemoglobin as a dynamic susceptibility contrast agent

ES Sayin, J Duffin, V Stumpo… - American Journal …, 2024 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Resting brain tissue perfusion in cerebral steno-occlusive
vascular disease can be assessed by MR imaging using gadolinium-based susceptibility …

[HTML][HTML] Quantifying cerebral blood arrival times using hypoxia-mediated arterial BOLD contrast

AA Bhogal, ES Sayin, J Poublanc, J Duffin, JA Fisher… - Neuroimage, 2022 - Elsevier
Cerebral blood arrival and tissue transit times are sensitive measures of the efficiency of
tissue perfusion and can provide clinically meaningful information on collateral blood flow …

Perfusion MRI using endogenous deoxyhemoglobin as a contrast agent: Preliminary data

J Poublanc, O Sobczyk, R Shafi… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To demonstrate the feasibility of mapping cerebral perfusion metrics with BOLD
MRI during modulation of pulmonary venous oxygen saturation. Methods A gas blender with …

[HTML][HTML] DSC MRI in the human brain using deoxyhemoglobin and gadolinium—Simulations and validations at 3T

JB Schulman, ES Sayin, A Manalac… - Frontiers in …, 2023 - frontiersin.org
Introduction Dynamic susceptibility contrast (DSC) MRI allows clinicians to determine
perfusion parameters in the brain, such as cerebral blood flow, cerebral blood volume, and …