Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Autoimmune diseases are usually complex and multifactorial, characterized by aberrant
production of autoreactive immune cells and/or autoantibodies against healthy cells and …

Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …

The prevalence of obesity, especially in women of child‐bearing age, is a global health
concern. In addition to increasing the immediate risk of gestational complications, there is …

An understanding of the events that initiate metabolic inflammation (metainflammation) can
support the identification of targets for preventing metabolic disease and its negative effects …

Background & Aims Obesity is an independent risk factor for malignancies, including
hepatocellular carcinoma (HCC). However, it remains unknown whether maternal obesity …

Obesity is reaching epidemic proportions and imposes major negative health crises and an
economic burden in both high and low income countries. The multifaceted nature of obesity …

Renal ischemia-reperfusion (I/R) injury is the most common cause of AKI, which associates
with high mortality and has no effective therapy. ELABELA (ELA) is a newly identified 32 …

Epigenetics is the study of mitotically or meiotically heritable phenotypes that occur as a
result of modifications to DNA, thereby regulating gene expression independently of …

In everyday clinical practice, healthcare professionals often meet chronic pain patients with
a poor nutritional status. A poor nutritional status such as malnutrition, unhealthy dietary …