[PDF][PDF] D. Goubert1, RAF Gjaltema1, 2, C. Huisman1, CPG Tobilla1, M. Koncz3, 4, PG Jellema1, 2, D. Wu1, U. Brouwer1, 2, A. Kiss3, PJ Verschure5, RA Bank2, MG …
D Goubert - Opportunities and Challenges of Epigenetic Editing in …, 2020 - research.rug.nl
Epigenetic Editing, an emerging technique used for the modulation of gene expression in
mammalian cells, is a promising strategy to correct disease-related gene expression …
mammalian cells, is a promising strategy to correct disease-related gene expression …
[PDF][PDF] Jonathan E. Sandoval1, 2, Yung-Hsin Huang1, Abigail Muise2, Margaret A. Goodell1
NO Reich - researchgate.net
Eukaryotic DNA methylation prevents genomic instability by regulating the expression of
oncogenes and tumorsuppressor genes. The negative effects of dysregulated DNA …
oncogenes and tumorsuppressor genes. The negative effects of dysregulated DNA …
Towards identification and targeting of Polycomb signaling pathways in leukemia
H Maat - 2019 - research.rug.nl
The development of leukemia is a multistep process that can be caused by multiple genetic
and epigenetic changes which affect normal growth and differentiation of hematopoietic …
and epigenetic changes which affect normal growth and differentiation of hematopoietic …
Modular Configuration of DEMETER DNA Demethylase and Its Application to Epigenome Editing
장호성 - 2019 - s-space.snu.ac.kr
DNA methylation is a key epigenetic modification which regulates gene expression and
chromatin structure in higher eukaryotes. DNA methylation is often mitotically heritable but …
chromatin structure in higher eukaryotes. DNA methylation is often mitotically heritable but …
Exploring the combinatorial effects of epigenetic modifiers upon the mammalian genome using CRISPR-dCas9
T Swain - 2020 - research-repository.uwa.edu.au
The epigenome consists of chemical modifications to DNA and histone proteins that can
regulate chromatin structure, DNA accessibility, and transcription. Given the complexity of …
regulate chromatin structure, DNA accessibility, and transcription. Given the complexity of …