A review of the potential effects of melatonin in compromised mitochondrial redox activities in elderly patients with COVID-19

WL Su, CC Wu, SFV Wu, MC Lee, MT Liao… - Frontiers in …, 2022 - frontiersin.org
Melatonin, an endogenous indoleamine, is an antioxidant and anti-inflammatory molecule
widely distributed in the body. It efficiently regulates pro-inflammatory and anti-inflammatory …

Melatonin and Covid-19: An opened Pandora's box and the hope for the time being

L Chacín-Bonilla, E Bonilla - Melatonin Research, 2023 - melatonin-research.net
The SARS-CoV-2 pandemic is a global health concern still ongoing. No single therapeutic
intervention with high efficacy exists and virus mutations continue to improve immune …

Assessing the antiviral potential of melatonin: A comprehensive systematic review

T Alomari, H Al‐Abdallat, R Hamamreh… - Reviews in Medical …, 2024 - Wiley Online Library
This review assesses the antiviral potential of melatonin through comprehensive analysis of
studies across human subjects, animal models, cell cultures, and in‐silico simulations. The …

Chitosan–sEPDM and Melatonin–Chitosan–sEPDM Composite Membranes for Melatonin Transport and Release

FM Păncescu, AAKK Rikabi, OC Oprea, AR Grosu… - Membranes, 2023 - mdpi.com
Melatonin is the hormone that focuses the attention of the researchers in the medical,
pharmaceutical, materials, and membranes fields due to its multiple biomedical implications …

Mechanism and role of mitophagy in the development of severe infection

L Ma, T Han, Y Zhan - Cell Death Discovery, 2024 - nature.com
Mitochondria produce adenosine triphosphate and potentially contribute to proinflammatory
responses and cell death. Mitophagy, as a conservative phenomenon, scavenges waste …

Antineoplastic indole-containing compounds with potential VEGFR inhibitory properties

DR Aboshouk, MA Youssef, MS Bekheit, AR Hamed… - RSC …, 2024 - pubs.rsc.org
Cancer is one of the most significant health challenges worldwide. Various techniques, tools
and therapeutics/materials have been developed in the last few decades for the treatment of …

Melatonin and redox homeostasis

S Süzen, MC Atayik, H Sirinzade… - Melatonin …, 2022 - melatonin-research.net
Redox homeostasis and redox signaling are constituents of preservation of a normal
physiological state. Whereas the equilibrium between oxidants and nucleophiles is …

[HTML][HTML] A mid‑pandemic night's dream: Melatonin, from harbinger of anti‑inflammation to mitochondrial savior in acute and long COVID‑19

IG Lempesis… - International …, 2024 - build.spandidos-publications.com
Abstract Coronavirus disease 2019 (COVID‑19), a systemic illness caused by severe acute
respiratory distress syndrome 2 (SARS‑CoV‑2), has triggered a worldwide pandemic with …

Beneficial effects of melatonin on liver fibrosis: A systematic review of current biological evidence

B San‐Miguel, P Fernández‐Palanca… - Journal of Cellular …, 2022 - Wiley Online Library
Hepatic fibrosis is a reversible response to either acute or chronic cellular injury from a wide
variety of etiologies, characterized by excessive deposition of extracellular matrix resulting in …

Melatonin: A review of its physiopathological and therapeutic relationship with parasitic diseases

RJ Cardenas, L Chacín-Bonilla… - Melatonin …, 2023 - melaonin-research.com
Melatonin (MEL), an indoleamine hormone synthesized in almost all organisms including
humans, has been the object of a considerable body of research due to its pleiotropic …