Astrocyte involvement in blood–brain barrier function: a critical update highlighting novel, complex, neurovascular interactions
Neurological disorders have been linked to a defective blood–brain barrier (BBB), with
dysfunctions triggered by stage-specific disease mechanisms, some of these being …
dysfunctions triggered by stage-specific disease mechanisms, some of these being …
[HTML][HTML] Role of primary aging hallmarks in Alzheimer´ s disease
J Zhao, J Huai - Theranostics, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …
threatens the health of the elderly and causes significant economic and social burdens. The …
Comparative analysis between 2D and 3D colorectal cancer culture models for insights into cellular morphological and transcriptomic variations
ZN Abbas, AZ Al-Saffar, SM Jasim, GM Sulaiman - Scientific Reports, 2023 - nature.com
Drug development is a time-consuming and expensive process, given the low success rate
of clinical trials. Now, anticancer drug developments have shifted to three-dimensional (3D) …
of clinical trials. Now, anticancer drug developments have shifted to three-dimensional (3D) …
Mesenchymal cells in the Lung: Evolving concepts and their role in fibrosis
Mesenchymal cells in the lung are crucial during development, but also contribute to the
pathogenesis of fibrotic disorders, including idiopathic pulmonary fibrosis (IPF), the most …
pathogenesis of fibrotic disorders, including idiopathic pulmonary fibrosis (IPF), the most …
[HTML][HTML] Epigenetic control of inflammation in Atopic Dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a common but also complex chronic,
itchy skin condition with underlying inflammation of the skin. This skin ailment is prevalent …
itchy skin condition with underlying inflammation of the skin. This skin ailment is prevalent …
[HTML][HTML] Comparative hepatotoxicity of novel lithium bis (trifluoromethanesulfonyl) imide (LiTFSI, ie. HQ-115) and legacy Perfluorooctanoic acid (PFOA) in male mice …
M Sands, X Zhang, M Laws, M Spinella… - Environment …, 2024 - Elsevier
Abstract Lithium Bis (trifluoromethanesulfonyl) imide (LiTFSI ie. HQ-115), a polymer
electrolyte used in energy applications, has been detected in the environment, yet its health …
electrolyte used in energy applications, has been detected in the environment, yet its health …
Mechanisms of human DNA methylation, alteration of methylation patterns in physiological processes and oncology
A Sergeeva, K Davydova, A Perenkov, M Vedunova - Gene, 2023 - Elsevier
DNA methylation is one of the epigenetic modifications of the genome, the essence of which
is the attachment of a methyl group to nitrogenous bases. In the eukaryote genome, cytosine …
is the attachment of a methyl group to nitrogenous bases. In the eukaryote genome, cytosine …
[HTML][HTML] Methylome-wide analysis of milk somatic cells upon subclinical mastitis in dairy cattle
Better understanding of the molecular mechanisms behind bovine mastitis is fundamental
for improving the management of this disease, which continues to be of major concern for …
for improving the management of this disease, which continues to be of major concern for …
[HTML][HTML] Targeted DNA methylation analysis and prediction of smoking habits in blood based on massively parallel sequencing
Tobacco smoking is a frequent habit sustained by> 1.3 billion people in 2020 and the
leading preventable factor for health risk and premature mortality worldwide. In the forensic …
leading preventable factor for health risk and premature mortality worldwide. In the forensic …
[HTML][HTML] Maternal SARS-CoV-2 exposure alters infant DNA methylation
Background Infection during pregnancy can increase the risk of neurodevelopmental
disorders in offspring. The impact of maternal SARS-CoV-2 infection on infant …
disorders in offspring. The impact of maternal SARS-CoV-2 infection on infant …