Research using human embryos and embryoids has expanded in recent years due to
technological advances. Surveying laws and guidelines among the top research and …

Gene therapy carries the potential to treat more than 10,000 human monogenic diseases
and benefit an even greater number of complex polygenic conditions. The repurposing of …

Gastrulation is a fundamental and critical process of animal development whereby the mass
of cells that results from the proliferation of the zygote transforms itself into a recognizable …

The “14‐day rule”—broadly construed—is used in science policy and regulation to limit
research on human embryos to a maximum period of 14 days after their creation or to the …

In this article, we discuss the ethics of human embryoids, ie, embryo-like structures made
from pluripotent stem cells for modeling natural embryos. We argue that defining our social …

This paper explores the ethics of introducing genome-editing technologies as a new
reproductive option. In particular, it focuses on whether genome editing can be considered a …

‘Ceci n’est pas un embryon?’ The ethics of human embryo model research | Nature Methods
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Background Breakthroughs in animal studies make the topic of human application of
ectogenesis for medical and non-medical purposes more relevant than ever before. While …

BACKGROUND Studying the human peri-implantation period remains hindered by the
limited accessibility of the in vivo environment and scarcity of research material. As such …

For the past 40 years, the 14-day rule has governed and, by defining a clear boundary,
enabled embryo research and the clinical benefits derived from this. It has been both a piece …