The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …

Dietary and other environmental factors induce epigenetic alterations which may have
important consequences for cancer development. This chapter summarizes current …

Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …

Ionizing radiation (IR) is a pivotal diagnostic and treatment modality, yet it is also a potent
genotoxic agent that causes genome instability and carcinogenesis. While modern cancer …

Remarkable progress in the field of epigenetics has turned academic, medical and public
attention to the potential applications of these new advances in medicine and various fields …

This review summarizes the carcinogenic mechanisms for 109 Group 1 human carcinogens
identified as causes of human cancer through Volume 106 of the IARC Monographs. The …

Epigenetics describes the study of stable, reversible alterations to the genome that affect
gene expression and genome function, the most studied mechanisms are DNA methylation …

Endocrine disrupting chemicals that are structurally similar to steroid or amine hormones
have the potential to mimic endocrine endpoints at the receptor level. However, more …

There is an increasing need to better understand the long-term health effects of high-linear
energy transfer (LET) radiation due to exposure during space missions, as well as its …