[HTML][HTML] DNA polymerases as useful reagents for biotechnology–the history of developmental research in the field
S Ishino, Y Ishino - Frontiers in microbiology, 2014 - frontiersin.org
DNA polymerase is a ubiquitous enzyme that synthesizes complementary DNA strands
according to the template DNA in living cells. Multiple enzymes have been identified from …
according to the template DNA in living cells. Multiple enzymes have been identified from …
[HTML][HTML] Comparative genomics of Archaea: how much have we learned in six years, and what's next?
KS Makarova, EV Koonin - Genome biology, 2003 - Springer
Archaea comprise one of the three distinct domains of life (with bacteria and eukaryotes).
With 16 complete archaeal genomes sequenced to date, comparative genomics has …
With 16 complete archaeal genomes sequenced to date, comparative genomics has …
[HTML][HTML] Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of …
TH Tahirov, KS Makarova, IB Rogozin, YI Pavlov… - Biology direct, 2009 - Springer
Background Evolution of DNA polymerases, the key enzymes of DNA replication and repair,
is central to any reconstruction of the history of cellular life. However, the details of the …
is central to any reconstruction of the history of cellular life. However, the details of the …
[HTML][HTML] The Archaeal DNA primase: biochemical characterization of the p41-p46 complex Frompyrococcus furiosus
L Liu, K Komori, S Ishino, AA Bocquier… - Journal of Biological …, 2001 - ASBMB
We characterized the primase complex of the hyperthermophilic archaeon, Pyrococcus
furiosus. The two proteins, Pfup41 and Pfup46, have similar sequences to the p48 and p58 …
furiosus. The two proteins, Pfup41 and Pfup46, have similar sequences to the p48 and p58 …
[HTML][HTML] Rapid progress of DNA replication studies in Archaea, the third domain of life
Y Ishino, S Ishino - Science China Life Sciences, 2012 - Springer
Archaea, the third domain of life, are interesting organisms to study from the aspects of
molecular and evolutionary biology. Archaeal cells have a unicellular ultrastructure without a …
molecular and evolutionary biology. Archaeal cells have a unicellular ultrastructure without a …
Biochemical Analysis of Replication Factor C from the Hyperthermophilic Archaeon Pyrococcus furiosus
IKO Cann, S Ishino, M Yuasa, H Daiyasu… - Journal of …, 2001 - Am Soc Microbiol
Replication factor C (RFC) and proliferating cell nuclear antigen (PCNA) are accessory
proteins essential for processive DNA synthesis in the domain Eucarya. The function of RFC …
proteins essential for processive DNA synthesis in the domain Eucarya. The function of RFC …
Pol B, a family B DNA polymerase, in Thermococcus kodakarensis is important for DNA repair, but not DNA replication
T Kushida, I Narumi, S Ishino, Y Ishino… - Microbes and …, 2019 - jstage.jst.go.jp
Thermococcus kodakarensis possesses two DNA polymerases, Pol B and Pol D. We
generated a T. kodakarensis strain (DPB1) in which polB was completely deleted and a …
generated a T. kodakarensis strain (DPB1) in which polB was completely deleted and a …
Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus
S Kiyonari, S Tahara, T Shirai, S Iwai… - Nucleic acids …, 2009 - academic.oup.com
Apurinic/apyrimidinic (AP) sites are the most frequently found mutagenic lesions in DNA,
and they arise mainly from spontaneous base loss or modified base removal by damage …
and they arise mainly from spontaneous base loss or modified base removal by damage …
Three Proliferating Cell Nuclear Antigen-Like Proteins Found in the Hyperthermophilic Archaeon Aeropyrum pernix: Interactions with the Two DNA Polymerases
K Daimon, Y Kawarabayasi, H Kikuchi… - Journal of …, 2002 - Am Soc Microbiol
Proliferating cell nuclear antigen (PCNA) is an essential component in the eukaryotic DNA
replication machinery, in which it works for tethering DNA polymerases on the DNA template …
replication machinery, in which it works for tethering DNA polymerases on the DNA template …
[HTML][HTML] Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy
K Mayanagi, K Oki, N Miyazaki, S Ishino, T Yamagami… - BMC biology, 2020 - Springer
Abstract Background DNA polymerase D (PolD) is the representative member of the D family
of DNA polymerases. It is an archaea-specific DNA polymerase required for replication and …
of DNA polymerases. It is an archaea-specific DNA polymerase required for replication and …