Drug-induced lupus
RL Yung, BC Richardson - Rheumatic disease clinics of North America, 1994 - Elsevier
Recent years have seen promising developments in both our appreciation of the spectrum of
autoimmune phenomena associated with DIL as well as our understanding of the …
autoimmune phenomena associated with DIL as well as our understanding of the …
Spermatogenesis: an overview
R Sharma, A Agarwal - … chromatin: biological and clinical applications in …, 2011 - Springer
The purpose of this chapter is to provide a comprehensive overview of spermatogenesis and
the various steps involved in the development of the male gamete, including cellular …
the various steps involved in the development of the male gamete, including cellular …
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter.
F Watt, PL Molloy - Genes & development, 1988 - genesdev.cshlp.org
Cytosine methylation within CpG dinucleotides has been implicated in the regulation of
gene expression in vertebrates and, in some cases, has been shown to be causative in …
gene expression in vertebrates and, in some cases, has been shown to be causative in …
Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
B Richardson, L Scheinbart, J Strahler… - … : Official Journal of …, 1990 - Wiley Online Library
Procainamide and hydralazine inhibit T cell DNA methylation and induce autoreactivity in
cloned CD4+ T cells. These drugs also induce an autoimmune syndrome, suggesting a …
cloned CD4+ T cells. These drugs also induce an autoimmune syndrome, suggesting a …
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2
M Comb, HM Goodman - Nucleic acids research, 1990 - academic.oup.com
DNA methylation at Hpall (CmCGG) sites inhibits expression of a human proenkephalin-
CAT fusion gene when it is transiently expressed in CV-1 cells or stably expressed in C6 …
CAT fusion gene when it is transiently expressed in CV-1 cells or stably expressed in C6 …
Inheritance of DNA methylation in Coprinus cinereus
ME Zolan, PJ Pukkila - Molecular and Cellular Biology, 1986 - Am Soc Microbiol
We examined the inheritance of 5-methylcytosine residues at a centromere-linked locus in
the basidiomycete Coprinus cinereus. Although methylated and unmethylated tracts were …
the basidiomycete Coprinus cinereus. Although methylated and unmethylated tracts were …
DNA methylation affects the formation of active chromatin
I Keshet, J Lieman-Hurwitz, H Cedar - Cell, 1986 - cell.com
To study the mechanism of gene repression by DNA methylation, Ml3 gene constructs were
methylated to completion and inserted into mouse L cells by DNA-mediated gene transfer …
methylated to completion and inserted into mouse L cells by DNA-mediated gene transfer …
Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in …
J Quddus, KJ Johnson, J Gavalchin… - The Journal of …, 1993 - Am Soc Clin Investig
Human antigen-specific CD4+ T cells become autoreactive after treatment with various DNA
methylation inhibitors, including 5-azacytidine, procainamide, and hydralazine. This …
methylation inhibitors, including 5-azacytidine, procainamide, and hydralazine. This …
Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse.
JP Sanford, HJ Clark, VM Chapman… - Genes & …, 1987 - genesdev.cshlp.org
We have examined the relative methylation levels of several dispersed repeated and low-
copy-number gene sequences during gametogenesis and early embryogenesis. Southern …
copy-number gene sequences during gametogenesis and early embryogenesis. Southern …
A single treatment of rice seedlings with 5-azacytidine induces heritable dwarfism and undermethylation of genomic DNA
H Sano, I Kamada, S Youssefian, M Katsumi… - Molecular and General …, 1990 - Springer
A single exposure of germinated rice seeds (Oryza sativa) to either of the DNA
demethylating agents 5-azacytidine (azaC) or 5-azadeoxycytidine (azadC) induced dwarf …
demethylating agents 5-azacytidine (azaC) or 5-azadeoxycytidine (azadC) induced dwarf …