OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …

The pathogenesis of intracranial aneurysms remains complex and multifactorial. While
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …

Wall shear stress, the frictional force of blood flow tangential to an artery lumen, has been
demonstrated in multiple studies to influence aneurysm formation and risk of rupture. In this …

Intracranial aneurysm (IA) is a severe cerebrovascular disease characterized by abnormal
bulging of cerebral vessels that may rupture and cause a stroke. The expansion of the …

Purpose Circumferential enhancement on MR vessel wall imaging has been proposed as a
biomarker of a higher risk of rupture in intracranial aneurysms. Focal enhancement is …

Computational blood flow modeling in intracranial aneurysms (IAs) has enormous potential
for the assessment of highly resolved hemodynamics and derived wall stresses. This results …

OBJECTIVE Aneurysm wall enhancement (AWE) on 3D vessel wall MRI (VWMRI) has been
suggested as an imaging biomarker for intracranial aneurysms (IAs) at higher risk of rupture …

Novel treatment strategies for cardiac tissue regeneration are heading for the use of
engineered cardiac tissue made from induced pluripotent stem cell-derived cardiomyocytes …

Computational fluid dynamics (CFD) simulations are increasingly utilised to evaluate
intracranial aneurysm (IA) haemodynamics to aid in the prediction of morphological changes …

The growth of cerebral aneurysms is linked to local hemodynamic conditions, but the driving
mechanisms of the growth are poorly understood. The goal of this study was to examine the …