Cell-free DNA-based liquid biopsies in neurology

H Gaitsch, RJM Franklin, DS Reich - Brain, 2023 - academic.oup.com
This article reviews recent developments in the application of cell-free DNA-based liquid
biopsies to neurological diseases. Over the past few decades, an explosion of interest in the …

Pan‐cancer analysis of the prognostic and immunological role of HSF1: a potential target for survival and immunotherapy

F Chen, Y Fan, P Cao, B Liu, J Hou… - … medicine and cellular …, 2021 - Wiley Online Library
Emerging evidence revealed the significant roles of heat shock factor 1 (HSF1) in cancer
initiation, development, and progression, but there is no pan‐cancer analysis of HSF1. The …

Towards a better understanding of TF-DNA binding prediction from genomic features

Z Wang, M Gong, Y Liu, S Xiong, M Wang… - Computers in Biology …, 2022 - Elsevier
Transcription factors (TFs) can regulate gene expression by recognizing specific cis-
regulatory elements in DNA sequences. TF-DNA binding prediction has become a …

[HTML][HTML] Large-scale transcriptome data analysis identifies KIF2C as a potential therapeutic target associated with immune infiltration in prostate cancer

P Zhang, H Gao, C Ye, R Yan, L Yu, C Xia… - Frontiers in …, 2022 - frontiersin.org
Prostate cancer (PCa) is one of the most prevalent cancers of the urinary system. In previous
research, Kinesin family member 2C (KIF2C), as an oncogene, has been demonstrated to …

[HTML][HTML] The regulation role and diagnostic value of fibrinogen-like protein 1 revealed by pan-cancer analysis

W Yi, T Qiao, Z Yang, L Hu, M Sun, H Fan, Y Xu, Z Lv - Materials Today Bio, 2022 - Elsevier
Although the role of fibrinogen-like protein 1 (FGL1) in tumorigenesis is well known, a pan-
cancer analysis of FGL1 lacks. We used bioinformatics techniques to analyze cancer data …

[HTML][HTML] SLC2As as diagnostic markers and therapeutic targets in LUAD patients through bioinformatic analysis

Y Zhang, H Qin, J Bian, Z Ma, H Yi - Frontiers in Pharmacology, 2022 - frontiersin.org
Facilitative glucose transporters (GLUTs), which are encoded by solute carrier 2A (SLC2A)
genes, are responsible for mediating glucose absorption. In order to meet their higher …

KIF11 as a potential pan‐cancer immunological biomarker encompassing the disease staging, prognoses, tumor microenvironment, and therapeutic responses

X Guo, L Zhou, Y Wu, J Li - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
KIF11 is one of the 45 family members of kinesin superfamily proteins that functions as a
motor protein in mitosis. Emerging evidence revealed that KIF11 plays pivotal roles in …

[HTML][HTML] High FLT3 expression indicates favorable prognosis and correlates with clinicopathological parameters and immune infiltration in breast cancer

R Chen, X Wang, J Fu, M Liang, T Xia - Frontiers in Genetics, 2022 - frontiersin.org
Purpose: Breast cancer is a highly heterogeneous malignancy, seriously threatening female
health worldwide and inducing higher mortalities. Few have the studies evaluated Fms-like …

[HTML][HTML] 同型半胱氨酸致胰岛β 细胞凋亡中肝配蛋白A 型受体2 DNA 甲基化升高

张晴, 高春兰, 于飞飞, 张正皓, 马芳, 高源, 李桂忠… - 中国组织工程研究, 2023 - cjter.com
摘要背景: 同型半胱氨酸水平增加会导致胰岛β 细胞发生凋亡, 但其具体机制尚不明确. 目的:
探讨胰岛β 细胞中肝配蛋白A 型受体2 及其启动子区DNA 高甲基化的具体机制. 方法 …

[HTML][HTML] A pan-cancer analysis of the role of USP5 in human cancers

B Yan, J Guo, S Deng, D Chen, M Huang - Scientific Reports, 2023 - nature.com
Posttranslational modifications (PTM) such as acetylation, deubiquitination, and
phosphorylation of proteins, play important roles in various kinds of cancer progression …