[HTML][HTML] Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: the role of Epstein–Barr virus and the gut–brain axis
K Hashimoto - Molecular Psychiatry, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …
[HTML][HTML] Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions
K Hashimoto - Molecular Psychiatry, 2023 - nature.com
The human body harbors a diverse ecosystem of microorganisms, including bacteria,
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …
[HTML][HTML] Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation
X Wang, Z Wang, J Cao, Y Dong, Y Chen - Microbiome, 2023 - Springer
Background Sleep loss is a serious global health concern. Consequences include memory
deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can …
deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can …
[HTML][HTML] Arketamine, a new rapid-acting antidepressant: a historical review and future directions
J Zhang, W Yao, K Hashimoto - Neuropharmacology, 2022 - Elsevier
The N-methyl-d-aspartate receptor (NMDAR) antagonist (R, S)-ketamine causes rapid onset
and sustained antidepressant actions in treatment-resistant patients with major depressive …
and sustained antidepressant actions in treatment-resistant patients with major depressive …
Fish disease and intestinal microbiota: A close and indivisible relationship
D Medina‐Félix, E Garibay‐Valdez… - Reviews in …, 2023 - Wiley Online Library
The gut microbiota is currently one of the most studied 'organs' in animals, and fish are no
exception. A complex diversity of microbes, including bacteria, archaea, yeast and fungus …
exception. A complex diversity of microbes, including bacteria, archaea, yeast and fungus …
[HTML][HTML] Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis
C Tan, Q Yan, Y Ma, J Fang, Y Yang - Frontiers in Neurology, 2022 - frontiersin.org
Depression is a worldwide disease causing severe disability, morbidity, and mortality.
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …
A role of gut–microbiota–brain axis via subdiaphragmatic vagus nerve in depression-like phenotypes in Chrna7 knock-out mice
The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7) is
known to regulate the cholinergic ascending anti-inflammatory pathway. We previously …
known to regulate the cholinergic ascending anti-inflammatory pathway. We previously …
[HTML][HTML] Arketamine for cognitive impairment in psychiatric disorders
K Hashimoto - European Archives of Psychiatry and Clinical …, 2023 - Springer
Cognitive impairment has been observed in patients with various psychiatric disorders,
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …
The microbiota–gut–brain axis and neurodevelopmental disorders
The gut microbiota has been found to interact with the brain through the microbiota–gut–
brain axis, regulating various physiological processes. In recent years, the impacts of the gut …
brain axis, regulating various physiological processes. In recent years, the impacts of the gut …
[HTML][HTML] Key role of the gut–microbiota–brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brain
Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central
nervous system. Dietary intake of cuprizone (CPZ) produces demyelination resembling that …
nervous system. Dietary intake of cuprizone (CPZ) produces demyelination resembling that …