[HTML][HTML] The placental epigenome as a molecular link between prenatal exposures and fetal health outcomes through the DOHaD hypothesis
S Lapehn, AG Paquette - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review The developmental origins of health and disease (DOHaD)
hypothesis posits that the perinatal environment can impact fetal and later life health. The …
hypothesis posits that the perinatal environment can impact fetal and later life health. The …
[HTML][HTML] In-utero exposure to air pollution and early-life neural development and cognition
Air pollution remains one of the major health threats around the world. Compared to adults,
foetuses and infants are more vulnerable to the effects of environmental toxins. Maternal …
foetuses and infants are more vulnerable to the effects of environmental toxins. Maternal …
[HTML][HTML] Prenatal air pollution exposure and placental DNA methylation changes: implications on fetal development and future disease susceptibility
The Developmental Origins of Health and Disease (DOHaD) concept postulates that in utero
exposures influence fetal programming and health in later life. Throughout pregnancy, the …
exposures influence fetal programming and health in later life. Throughout pregnancy, the …
Select early-life environmental exposures and DNA methylation in the placenta
M Mortillo, CJ Marsit - Current environmental health reports, 2023 - Springer
Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …
exposures on DNA methylation in the placenta, to identify how variation in placental …
[HTML][HTML] Life-course exposure to air pollution and biological ageing in the Lothian Birth Cohort 1936
Background Exposure to air pollution is associated with a range of diseases. Biomarkers
derived from DNA methylation (DNAm) offer potential mechanistic insights into human …
derived from DNA methylation (DNAm) offer potential mechanistic insights into human …
[HTML][HTML] A role for gene-environment interactions in autism spectrum disorder is supported by variants in genes regulating the effects of exposure to xenobiotics
JX Santos, C Rasga, AR Marques… - Frontiers in …, 2022 - frontiersin.org
Heritability estimates support the contribution of genetics and the environment to the etiology
of Autism Spectrum Disorder (ASD), but a role for gene-environment interactions is …
of Autism Spectrum Disorder (ASD), but a role for gene-environment interactions is …
[HTML][HTML] Placental transcriptomic signatures of prenatal exposure to Hydroxy-Polycyclic aromatic hydrocarbons
Abstract Background Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants
originating from petrogenic and pyrogenic sources. PAH compounds can cross the placenta …
originating from petrogenic and pyrogenic sources. PAH compounds can cross the placenta …
Cohort Profile: The Shanghai Maternal-Child Pairs Cohort (MCPC)
Y Gui, Y Zhao, XG Tao, W Xu, Q Yang… - International Journal …, 2024 - academic.oup.com
Numerous studies have increasingly demonstrated that the aetiology of chronic diseases,
including autism, hyperactivity, asthma, diabetes, obesity and cardiovascular diseases, can …
including autism, hyperactivity, asthma, diabetes, obesity and cardiovascular diseases, can …
[HTML][HTML] Placental transcriptomic signatures of prenatal and preconceptional maternal stress
Prenatal exposure to maternal psychological stress is associated with increased risk for
adverse birth and child health outcomes. Accumulating evidence suggests that …
adverse birth and child health outcomes. Accumulating evidence suggests that …
Prenatal exposure of organophosphate esters and its trimester-specific and gender-specific effects on fetal growth
H Wang, P Wang, Q Li, J Li, L Zhang… - Environmental …, 2022 - ACS Publications
The toxicity of organophosphate esters (OPEs) on embryonic development is well noted in
animal experiments, but epidemiological studies are still lacking. This study evaluated the …
animal experiments, but epidemiological studies are still lacking. This study evaluated the …