A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Rational design and latest advances of polysaccharide-based hydrogels for wound healing

H Hu, FJ Xu - Biomaterials science, 2020 - pubs.rsc.org
Acute and chronic wounds cause severe physical trauma to patients and also bring an
immense socio-economic burden. Hydrogels are considered to be effective wound …

[HTML][HTML] The role of extracelluar matrix in osteosarcoma progression and metastasis

J Cui, D Dean, FJ Hornicek, Z Chen, Z Duan - Journal of Experimental & …, 2020 - Springer
Osteosarcoma (OS) is the most common primary bone malignancy and responsible for
considerable morbidity and mortality due to its high rates of pulmonary metastasis. Although …

Crosstalk between Sertoli and germ cells in male fertility

S Wu, M Yan, R Ge, CY Cheng - Trends in molecular medicine, 2020 - cell.com
Spermatogenesis is supported by intricate crosstalk between Sertoli cells and germ cells
including spermatogonia, spermatocytes, haploid spermatids, and spermatozoa, which …

[HTML][HTML] Main and minor types of collagens in the articular cartilage: the role of collagens in repair tissue evaluation in chondral defects

L Alcaide-Ruggiero, V Molina-Hernández… - International Journal of …, 2021 - mdpi.com
Several collagen subtypes have been identified in hyaline articular cartilage. The main and
most abundant collagens are type II, IX and XI collagens. The minor and less abundant …

[HTML][HTML] Biochemical markers of musculoskeletal health and aging to be assessed in clinical trials of drugs aiming at the treatment of sarcopenia: consensus paper …

A Ladang, C Beaudart, JY Reginster… - Calcified Tissue …, 2023 - Springer
In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

[HTML][HTML] Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche

SC Schüler, Y Liu, S Dumontier… - Frontiers in Cell and …, 2022 - frontiersin.org
The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …

Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound via anti …

L Long, W Liu, L Li, C Hu, S He, L Lu, J Wang, L Yang… - Nanoscale, 2022 - pubs.rsc.org
Nowadays, diabetic chronic wounds impose a heavy burden on patients and the medical
system. Persistent inflammation and poor tissue remodeling severely limit the healing of …

[HTML][HTML] Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating …

S Li, J Liu, S Liu, W Jiao, X Wang - Journal of Nanobiotechnology, 2021 - Springer
Objectives This study aimed to investigate the roles of adipose mesenchymal stem cell
(AMSC)-derived extracellular vesicles (EVs) binding with chitosan oligosaccharides (COS) …