Silencing of COL3A1 represses proliferation, migration, invasion, and immune escape of triple negative breast cancer cells via down‐regulating PD‐L1 expression

F Yang, L Lin, X Li, R Wen, X Zhang - Cell Biology International, 2022 - Wiley Online Library
This study is designed to illuminate the specific role and underlying mechanism of collagen
type III alpha 1 chain (COL3A1) in triple negative breast cancer (TNBC). Quantitative real …

Proteomic characterization of collagen-based animal glues for restoration

G Ntasi, S Sbriglia, R Pitocchi… - Journal of proteome …, 2022 - ACS Publications
Animal glues are widely used in restoration as adhesives, binders, and consolidants for
organic and inorganic materials. Their variable performances are intrinsically linked to the …

[HTML][HTML] Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics …

J Ding, Y Liu, Y Lai - PeerJ, 2020 - peerj.com
Background Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant neoplasm. It is
necessary to improve the understanding of the underlying molecular mechanisms and …

Dynamic dentin: A quantitative microscopic assessment of age and spatial changes to matrix architecture, peritubular dentin, and collagens types I and III

AT Weerakoon, N Condon, TR Cox, C Sexton… - Journal of Structural …, 2022 - Elsevier
To investigate age and site-related changes to human dentin collagen, sound human teeth
collected from donors aged 13–29 (young) and 50–74 (aged) years (n= 9/group) were cut to …

[HTML][HTML] Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer

G Yao, K Zhao, K Bao, J Li - Open Medicine, 2022 - degruyter.com
Background Radiotherapy-associated secondary cancer is an important issue for the
treatment of breast cancer (BCa). This study aimed to investigate the molecular mechanism …

COL3A1, COL5A1 and COL6A2 serve as potential molecular biomarkers for osteoarthritis based on weighted gene co‑expression network analysis bioinformatics …

Y Zhang, Y Niu, Y Peng, X Pan… - Experimental and …, 2023 - spandidos-publications.com
Osteoarthritis (OA) is a non‑inflammatory degenerative joint disease, characterized by joint
pain and stiffness. The prevalence of OA increases with age. However, the relationship …

Morphofunctional and histological patterns of blood vessels in the superficial cervicofacial musculoaponeurotic system in midlateral face regions

RP Cucu, MV Hînganu, VV Costan, L Lozneanu… - Annals of Anatomy …, 2024 - Elsevier
Objective The superficial cervicofacial musculoaponeurotic system (SMAS) is a complex
network formed by mimic muscles and conjunctive tissue of the superficial fascia of the face …

[HTML][HTML] The Activation of the LIMK/Cofilin Signaling Pathway via Extracellular Matrix–Integrin Interactions Is Critical for the Generation of Mature and Vascularized …

JM Noh, SC Choi, MH Song, KS Kim, S Jun, JH Park… - Cells, 2023 - mdpi.com
The generation of mature and vascularized human pluripotent stem cell-derived cardiac
organoids (hPSC-COs) is necessary to ensure the validity of drug screening and disease …

[HTML][HTML] Context matters: Response heterogeneity to collagen-targeting approaches in desmoplastic cancers

AM Fuller, TSK Eisinger-Mathason - Cancers, 2022 - mdpi.com
Simple Summary A common feature of tumor types such as breast cancer, prostate cancer,
pancreatic cancer, and soft-tissue sarcoma is the deposition of collagen-rich tissue called …

LncRNA H19 regulates proliferation, apoptosis and ECM degradation of aortic smooth muscle cells via miR-1-3p/ADAM10 axis in thoracic aortic aneurysm

Z Fan, S Liu, H Zhou - Biochemical Genetics, 2022 - Springer
Thoracic aortic aneurysm (TAA) is a prevalent health problem worldwide. Long non-coding
RNA H19was highly expressed in TAA patients, but the function and mechanism of H19 in …