[HTML][HTML] First Characterization of the Transcriptome of Lung Fibroblasts of SSc Patients and Healthy Donors of African Ancestry

L Renaud, KM Waldrep, WA da Silveira… - International Journal of …, 2023 - mdpi.com
Systemic sclerosis (SSc) is a connective tissue disorder that results in fibrosis of the skin and
visceral organs. SSc-associated pulmonary fibrosis (SSc-PF) is the leading cause of death …

[HTML][HTML] Collagen Type III as a Possible Blood Biomarker of Fibrosis in Equine Endometrium

J Alpoim-Moreira, C Fernandes, MR Rebordão… - Animals, 2022 - mdpi.com
Simple Summary In the mare, endometrosis is a disease characterized by excessive
collagen fibers deposition in the endometrium (uterus inner layer), which is responsible for …

An endometrial biomimetic extracellular matrix (ECM) for enhanced endometrial regeneration using hyaluronic acid hydrogel containing recombinant human type III …

S Wei, Z Li, H Xia, Z Wang, J Deng, L Li… - International Journal of …, 2024 - Elsevier
Endometrial injury poses a significant challenge in tissue regeneration, with type III collagen
(COL III) playing a pivotal role in maintaining endometrial integrity and facilitating repair. Our …

Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Rheumatoid Arthritis Symptoms via Shuttling Proteins

L Wang, F Li, L Wang, B Wu, M Du… - Journal of Proteome …, 2024 - ACS Publications
Our prior investigations have evidenced that bone marrow mesenchymal stem cell (BMSC)
therapy can significantly improve the outcomes of rheumatoid arthritis (RA). This study aims …

Tissue inhibitor of metalloproteinase-4 deletion in mice impacts maternal cardiac function during pregnancy and postpartum

AA Thurstin, AN Egeli, EC Goldsmith… - American Journal …, 2023 - journals.physiology.org
Reversible physiological cardiac hypertrophy of the maternal heart occurs during pregnancy
and involves extracellular matrix (ECM) remodeling. Previous mouse studies revealed that …

[HTML][HTML] Identification of cellular heterogeneity and key signaling pathways associated with vascular remodeling and calcification in young and old primate aortas …

Y Yin, C Huang, Z Wang, P Huang, S Qin - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Aging of the vascular system is the main cause of many cardiovascular diseases. The
structure and function of the blood vessel wall change with aging. To prevent age-related …

[HTML][HTML] Evaluating perinatal and neonatal outcomes among children with vascular Ehlers–Danlos syndrome

SB Stephens, M Russo, S Shalhub, T Beecroft… - Genetics in …, 2022 - Elsevier
Purpose Birth outcomes data for patients with vascular Ehlers–Danlos syndrome (VEDS) are
limited. Methods Patients with a pathogenic or likely pathogenic COL3A1 variant were …

Genetic architecture of thoracic aortic dissection in the female population

Y Chen, L Wang, X Xu, K Li, Y Sun, Y Wang, DW Wang - Gene, 2023 - Elsevier
Background Sex-related differences in cardiovascular disease are now gaining much more
attention and their importance is increasingly being recognized, but little is known about the …

Quantitative evaluation of human umbilical vein and induced pluripotent stem cell-derived endothelial cells as an alternative cell source to skin-specific endothelial …

A Pappalardo, L Herron… - Advances in Wound …, 2021 - liebertpub.com
Objective: We compared the capability of human umbilical vein endothelial cells (HUVECs),
induced pluripotent stem cell (iPSC)-derived endothelial cells (iECs), and human dermal …

The collagen superfamily: everything you always wanted to know

M Salamito, P Nauroy, F Ruggiero - The collagen superfamily and …, 2021 - Springer
Collagens are the most abundant extracellular matrix proteins in multicellular organisms. In
humans, the collagen superfamily counts 28 proteins encoded by 44 genes whose functions …