[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
DNA methylation plays a vital role in epigenetic regulation in both plants and animals, and
typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …

[HTML][HTML] Whole genome DNA methylation: beyond genes silencing

R Tirado-Magallanes, K Rebbani, R Lim, S Pradhan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The combination of DNA bisulfite treatment with high-throughput sequencing technologies
has enabled investigation of genome-wide DNA methylation at near base pair level …

[HTML][HTML] Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability

TTM Ngo, J Yoo, Q Dai, Q Zhang, C He… - Nature …, 2016 - nature.com
Cytosine can undergo modifications, forming 5-methylcytosine (5-mC) and its oxidized
products 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxylcytosine …

[HTML][HTML] Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis

MT Dyson, D Roqueiro, D Monsivais, CM Ercan… - PLoS …, 2014 - journals.plos.org
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-
like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit …

[HTML][HTML] Dnmt1-independent CG methylation contributes to nucleosome positioning in diverse eukaryotes

JT Huff, D Zilberman - Cell, 2014 - cell.com
Dnmt1 epigenetically propagates symmetrical CG methylation in many eukaryotes. Their
genomes are typically depleted of CG dinucleotides because of imperfect repair of …

DNA methylation as a transcriptional regulator of the immune system

L Morales-Nebreda, FS McLafferty, BD Singer - Translational Research, 2019 - Elsevier
DNA methylation is a dynamic epigenetic modification with a prominent role in determining
mammalian cell development, lineage identity, and transcriptional regulation. Primarily …

5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells

EA Raiber, G Portella, S Martínez Cuesta, R Hardisty… - Nature …, 2018 - nature.com
Nucleosomes are the basic unit of chromatin that help the packaging of genetic material
while controlling access to the genetic information. The underlying DNA sequence, together …

DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes

DB Lyons, D Zilberman - Elife, 2017 - elifesciences.org
Cytosine methylation regulates essential genome functions across eukaryotes, but the
fundamental question of whether nucleosomal or naked DNA is the preferred substrate of …

[PDF][PDF] DNA methylation cues in nucleosome geometry, stability, and unwrapping

S Li, Y Peng, D Landsman, A Panchenko - Biophysical Journal, 2022 - cell.com
2532-Pos A study on alterations in membrane physiology of human erythrocytes due to
extracellular tonicity through dielectrophoresis Jogu Sumathi, Mohd Abdul Saleem, Adeel …

[HTML][HTML] Alternative splicing, epigenetic modifications and cancer: a dangerous triangle, or a hopeful one?

F Gimeno-Valiente, G López-Rodas, J Castillo… - Cancers, 2022 - mdpi.com
Simple Summary Epigenetics studies the alteration of gene expression without changing
DNA sequence and very often, epigenetic dysregulation causes cancer. Alternative splicing …