Preventive strategies for mental health

C Arango, CM Díaz-Caneja, PD McGorry… - The Lancet …, 2018 - thelancet.com
Available treatment methods have shown little effect on the burden associated with mental
health disorders. We review promising universal, selective, and indicated preventive mental …

Autism genetics: opportunities and challenges for clinical translation

JAS Vorstman, JR Parr, D Moreno-De-Luca… - Nature Reviews …, 2017 - nature.com
Genetic studies have revealed the involvement of hundreds of gene variants in autism. Their
risk effects are highly variable, and they are frequently related to other conditions besides …

Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders

SE Soden, CJ Saunders, LK Willig, EG Farrow… - Science translational …, 2014 - science.org
Neurodevelopmental disorders (NDDs) affect more than 3% of children and are attributable
to single-gene mutations at more than 1000 loci. Traditional methods yield molecular …

Population impact of preterm birth and low birth weight on developmental disabilities in US children

LA Schieve, LH Tian, K Rankin, MD Kogan… - Annals of …, 2016 - Elsevier
Purpose Although previous studies demonstrate associations between adverse perinatal
outcomes and developmental disabilities (DDs), study of population impacts is limited …

[HTML][HTML] A genetic investigation of sex bias in the prevalence of attention-deficit/hyperactivity disorder

J Martin, RK Walters, D Demontis, M Mattheisen… - Biological …, 2018 - Elsevier
Background Attention-deficit/hyperactivity disorder (ADHD) shows substantial heritability
and is two to seven times more common in male individuals than in female individuals. We …

A framework for an evidence-based gene list relevant to autism spectrum disorder

CP Schaaf, C Betancur, RKC Yuen, JR Parr… - Nature Reviews …, 2020 - nature.com
Autism spectrum disorder (ASD) is often grouped with other brain-related phenotypes into a
broader category of neurodevelopmental disorders (NDDs). In clinical practice, providers …

Autism spectrum disorder and attention-deficit/hyperactivity disorder in early childhood: A review of unique and shared characteristics and developmental antecedents

JC Visser, NNJ Rommelse, CU Greven… - … & Biobehavioral Reviews, 2016 - Elsevier
Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have
overlapping characteristics and etiological factors, but to which extent this applies to infant …

The comorbidity of ADHD and autism spectrum disorder

KM Antshel, Y Zhang-James… - Expert review of …, 2013 - Taylor & Francis
ADHD and autism spectrum disorder are common psychiatric comorbidities to each another.
In addition, there is behavioral, biological and neuropsychological overlap between the two …

The developmental stages of synaptic plasticity

C Lohmann, HW Kessels - The Journal of physiology, 2014 - Wiley Online Library
The brain is programmed to drive behaviour by precisely wiring the appropriate neuronal
circuits. Wiring and rewiring of neuronal circuits largely depends on the orchestrated …

[HTML][HTML] A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11. 2 deletion syndrome

AM Fiksinski, GD Hoftman, JAS Vorstman… - Molecular …, 2023 - nature.com
Recently, increasing numbers of rare pathogenic genetic variants have been identified that
are associated with variably elevated risks of a range of neurodevelopmental outcomes …