[HTML][HTML] The epitranscriptome of high-grade gliomas: a promising therapeutic target with implications from the tumor microenvironment to endogenous retroviruses

CK Ramsoomair, M Ceccarelli, JD Heiss… - Journal of Translational …, 2023 - Springer
Abstract Glioblastoma (GBM) comprises 45.6% of all primary malignant brain cancers and is
one of the most common and aggressive intracranial tumors in adults. Intratumoral …

[HTML][HTML] The rise of epitranscriptomics: recent developments and future directions

J Cerneckis, GL Ming, H Song, C He, Y Shi - Trends in Pharmacological …, 2023 - cell.com
The epitranscriptomics field has undergone tremendous growth since the discovery that the
RNA N 6-methyladenosine (m 6 A) modification is reversible and is distributed throughout …

[HTML][HTML] METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity

BWL Lee, YH Chuah, J Yoon, OV Grinchuk… - Cell Death & …, 2024 - nature.com
Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells
(GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (m3C) is a new …

[HTML][HTML] Role of N6-methyladenosine methylation in glioma: recent insights and future directions

C Li, B Li, H Wang, L Qu, H Liu, C Weng, J Han… - Cellular & Molecular …, 2023 - Springer
Glioma is the most pervasive intracranial tumor in the central nervous system (CNS), with
glioblastoma (GBM) being the most malignant type having a highly heterogeneous cancer …

Nanoparticles for efficient drug delivery and drug resistance in glioma: New perspectives

J Liu, F Yang, J Hu, X Zhang - CNS Neuroscience & …, 2024 - Wiley Online Library
Gliomas are the most common primary tumors of the central nervous system, with
glioblastoma multiforme (GBM) having the highest incidence, and their therapeutic efficacy …

Research progress on function and mechanism of long non-coding RNA in glioma

F Tai, X Zhao - Cellular and Molecular Biology, 2024 - cellmolbiol.org
This review aimed to comprehensively summarize the role of long non-coding RNA
(lncRNA) in gliomas, the most common malignant tumors in the central nervous system, and …

Application of RNA-based therapeutics in glioma: A review.

M Sanati, AR Afshari, SS Ahmadi… - Progress in Molecular …, 2023 - europepmc.org
Despite the extensive advancements made in the field of cancer therapy, the outlook of
individuals suffering from glioblastoma multiforme remains highly detrimental. The absence …