Background Drugs can prevent postoperative nausea and vomiting, but their relative
efficacies and side effects have not been compared within one systematic review. Objectives …

Preoperative anxiety (anxiety regarding impending surgical experience) in children is a
common phenomenon that has been associated with a number of negative behaviors during …

Comprehensive, readable, and clinically oriented, Stoelting's Pharmacology & Physiology in
Anesthetic Practice, Sixth Edition, covers all aspects of pharmacology and physiology that …

BACKGROUND: Midazolam is the most commonly used premedication in children. It has
been shown to be more effective than parental presence or placebo in reducing anxiety and …

Interventions The purpose of preoperative anxiolysis is to reduce a child's anxiety and
decrease the risk of negative postoperative behavioral changes. Preoperative anxiolysis …

Behind the multiple arguments for and against the use of premedication, sedative drugs in
children is a noble principle that of minimizing psychological trauma related to anesthesia …

The selection and design of age-appropriate formulations intended for use in paediatric and
geriatric patients are dependent on multiple factors affecting patient acceptability, safety and …

BACKGROUND: Distraction technology suitable for the perioperative setting is readily
available, but there is little evidence to show how it compares with oral midazolam in …

GABA is the major inhibitory neurotransmitter in the central nervous system (CNS). The type
A GABA receptor (GABAAR) system is the primary pharmacological target for many drugs …

One of the most widely used options for minimal/moderate sedation in pediatric patients is
oral midazolam, as it presents an alternative to less well‐accepted routes of administration …