Left atrial fibrosis in atrial fibrillation: Mechanisms, clinical evaluation and management

J Ma, Q Chen, S Ma - Journal of cellular and molecular …, 2021 - Wiley Online Library
Atrial fibrillation (AF), the commonest arrhythmia, shows associations with various disease
conditions. Mounting evidence indicates that atrial fibrosis is an important part of the …

[HTML][HTML] The combination of beta-blockers and ACE inhibitors across the spectrum of cardiovascular diseases

MH Strauss, AS Hall, K Narkiewicz - Cardiovascular Drugs and Therapy, 2023 - Springer
Cardiovascular disease is the leading cause of mortality worldwide, affecting a wide range
of patients at different stages across the cardiovascular continuum. Hypertension is one of …

Systematic identification of trans eQTLs as putative drivers of known disease associations

HJ Westra, MJ Peters, T Esko, H Yaghootkar… - Nature …, 2013 - nature.com
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta …

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2013)–Digest Version–

JCS Joint Working Group - Circulation Journal, 2014 - jstage.jst.go.jp
The present guidelines are a revision of the 2008 version of Guidelines for
Pharmacotherapy of Atrial Fibrillation, 1 which were originally published in 2001, 2 and …

New gene functions in megakaryopoiesis and platelet formation

C Gieger, A Radhakrishnan, A Cvejic, W Tang, E Porcu… - Nature, 2011 - nature.com
Platelets are the second most abundant cell type in blood and are essential for maintaining
haemostasis. Their count and volume are tightly controlled within narrow physiological …

Diabetes mellitus, glycemic control, and risk of atrial fibrillation

S Dublin, NL Glazer, NL Smith, BM Psaty… - Journal of general …, 2010 - Springer
BACKGROUND Diabetes may be an independent risk factor for atrial fibrillation. However,
results from prior studies are in conflict, and no study has examined diabetes duration or …

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

SA Lubitz, KL Lunetta, H Lin, DE Arking… - Journal of the American …, 2014 - jacc.org
Objectives: This study sought to identify nonredundant atrial fibrillation (AF) genetic
susceptibility signals and examine their cumulative relations with AF risk. Background: AF …

Lower risk of cardiovascular events in postmenopausal women taking oral estradiol compared with oral conjugated equine estrogens

NL Smith, M Blondon, KL Wiggins… - JAMA internal …, 2014 - jamanetwork.com
Importance Little is known about the comparative cardiovascular safety of oral hormone
therapy products, which impedes women from making informed safety decisions about …

Randomized trial of angiotensin II-receptor blocker vs. dihydropiridine calcium channel blocker in the treatment of paroxysmal atrial fibrillation with hypertension (J …

T Yamashita, H Inoue, K Okumura, I Kodama… - Europace, 2011 - academic.oup.com
Aims Atrial fibrillation (AF) is a common arrhythmia frequently associated with hypertension.
This study was designed to test the hypothesis that lowering blood pressure by angiotensin …

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

NL Smith, KM Rice, EG Bovill… - Blood, The Journal …, 2011 - ashpublications.org
In a recent genome-wide association study, variants in 8 genes were associated with VWF
level, a risk factor for venous thrombosis (VT). In an independent, population-based, case …