Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …

The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

Human trophoblast stem cells (hTSCs) provide a valuable model to study placental
development and function. While primary hTSCs have been derived from embryos/early …

The human placenta has a vital role in ensuring a successful pregnancy. Despite the
growing body of knowledge about its cellular compositions and functions, there has been …

The uterine lining (endometrium) regenerates repeatedly over the life span as part of its
normal physiology. Substantial portions of the endometrium are shed during childbirth …

The basic body plan of the mammalian embryo is established through gastrulation, a pivotal
early postimplantation event during which the three major germ layers (endoderm …

CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …

Infection by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) results in
the novel coronavirus disease COVID-19, which has posed a serious threat globally …

Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

Remodeling of the uterine vasculature by invasive extravillous trophoblasts (EVTs) is a
critical aspect of human placentation. Insufficient EVT invasion can lead to severe obstetrical …