Distinct Mechanisms of β-Arrestin–Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality
ZP Jara, TJ Harford, KD Singh, R Desnoyer… - …, 2023 - Am Heart Assoc
Background: Aortic aneurysm (AA) is a “silent killer” human disease with no effective
treatment. Although the therapeutic potential of various pharmacological agents have been …
treatment. Although the therapeutic potential of various pharmacological agents have been …
Pathogenic and therapeutic significance of angiotensin II type I receptor in abdominal aortic aneurysms
Background: Abdominal aortic aneurysm (AAA) is a chronic degenerative inflammatory
disease. Multi-factors including genetic, environmental and lifestyle factors determine the …
disease. Multi-factors including genetic, environmental and lifestyle factors determine the …
Antiplatelet Therapy, Abdominal Aortic Aneurysm Progression, and Clinical Outcomes
Importance Preclinical studies suggest a potential role for aspirin in slowing abdominal
aortic aneurysm (AAA) progression and preventing rupture. Evidence on the clinical benefit …
aortic aneurysm (AAA) progression and preventing rupture. Evidence on the clinical benefit …
Association of Life's Simple 7 with reduced clinically manifest abdominal aortic aneurysm: the ARIC study
AO Oyenuga, AR Folsom, PL Lutsey… - Vascular …, 2019 - journals.sagepub.com
To optimize cardiovascular health, the American Heart Association (AHA) has
recommended 'Life's Simple 7 (LS7)'. We tested the hypothesis that greater adherence to the …
recommended 'Life's Simple 7 (LS7)'. We tested the hypothesis that greater adherence to the …
Genetics of Aortic Diseases
AA Roscher, RA Dieter, TD Raabe - Diseases of the Aorta, 2019 - Springer
The clinically most important aortic diseases are those that cause aneurysms and
dissections in the aortic wall. Aortic aneurysms and/or dissections are sometimes subject to …
dissections in the aortic wall. Aortic aneurysms and/or dissections are sometimes subject to …