Abstract Background The International Society on Thrombosis and Haemostasis (ISTH)
released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001 …

Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and
microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the …

Acute respiratory failure and a systemic coagulopathy are critical aspects of the morbidity
and mortality characterizing infection with severe acute respiratory distress syndrome …

Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) refers to the thrombotic
microangiopathy resulting from uncontrolled complement activation during pregnancy or the …

Atypical hemolytic uremic syndrome (aHUS) is a rare, genetic, life-threatening disease. The
Global aHUS Registry collects real-world data on the natural history of the disease. Here we …

The membrane attack complex—also known as C5b-9—is the end-product of the classical,
lectin, and alternative complement pathways. It is thought to play an important role in the …

Involvement of the alternative complement pathway (AP) in microvascular endothelial cell
(MVEC) injury characteristic of a thrombotic microangiopathy (TMA) is well documented …

The syndrome of thrombotic microangiopathy (TMA) is a clinical-pathological entity
characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end organ …

Thrombocytopenia affects 25–55% of intensive care unit (ICU) patients [1]. The reasons for
thrombocytopenia in the ICU are numerous, including, among others, sepsis, drugs, and the …

Thrombotic microangiopathy (TMA) is defined by specific clinical characteristics, including
microangiopathic hemolytic anemia, thrombocytopenia, and pathologic evidence of …