Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

VX Han, S Patel, HF Jones, RC Dale - Nature Reviews Neurology, 2021 - nature.com
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review

VX Han, S Patel, HF Jones, TC Nielsen… - Translational …, 2021 - nature.com
Inflammation is increasingly recognized as a cause or consequence of common problems of
humanity including obesity, stress, depression, pollution and disease states such as …

After asthma: redefining airways diseases

ID Pavord, R Beasley, A Agusti, GP Anderson, E Bel… - The Lancet, 2018 - thelancet.com
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

Asthma: definitions and pathophysiology

JW Mims - International forum of allergy & rhinology, 2015 - Wiley Online Library
Background Asthma is a common condition due to chronic inflammation of the lower
respiratory tract. Chronic lower airway inflammation is known to be more common in …

Sex bias in asthma prevalence and pathogenesis

R Shah, DC Newcomb - Frontiers in immunology, 2018 - frontiersin.org
Sex-related differences in asthma prevalence are well established and change through the
reproductive phases of life. As children, boys have increased prevalence of asthma …

The role of epigenetic change in autism spectrum disorders

YJ Loke, AJ Hannan, JM Craig - Frontiers in neurology, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …

Epigenetics and autism spectrum disorder: Is there a correlation?

AA Eshraghi, G Liu, SIS Kay, RS Eshraghi… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) is the term for a range of development disorders caused by
a combination of genetic and environmental factors (Kubota et al., 2012; Loke et al., 2015; …

Systems biology of asthma and allergic diseases: a multiscale approach

S Bunyavanich, EE Schadt - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
Systems biology is an approach to understanding living systems that focuses on modeling
diverse types of high-dimensional interactions to develop a more comprehensive …

Asthma outcomes and management during pregnancy

CA Bonham, KC Patterson, ME Strek - Chest, 2018 - Elsevier
Asthma during pregnancy poses a common, increasingly prevalent threat to the health of
women and their children. The present article reviews recent insights gained from the …

Epigenetics in asthma

JL Gomez - Current allergy and asthma reports, 2019 - Springer
Abstract Purpose of Review Asthma is one of the most common chronic respiratory diseases
linked with increased morbidity and healthcare utilization. The underlying …