In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Cadmium is an environmental pollutant known as endocrine disruptor. Testis is particularly
susceptible to cadmium, and testis injury occurs at high but even low levels of exposure …

Male obesity in reproductive-age men has nearly tripled in the past 30 y and coincides with
an increase in male infertility worldwide. There is now emerging evidence that male obesity …

OBJECTIVE: To review and summarize the current understanding of the epigenetic status of
human sperm in regards to protamination, specific localization and modifications of retained …

Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …

Considering the widespread use of assisted reproductive techniques (ART), DNA
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …

Worldwide obesity rates have nearly doubled since 1980 and currently over 10% of the
population is obese. In 2008, over 1.4 billion adults aged 20 years and older had a body …

Infertility is a complex disorder with multiple genetic and environmental causes. Although
some specific mutations have been identified, other factors responsible for sperm defects …

BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

Abstract The Sixth Evian Annual Reproduction (EVAR) Workshop Group Meeting was held
to evaluate the impact of IVF/intracytoplasmic sperm injection on the health of assisted …