Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

Recent studies have indicated that epigenetic alterations are critical for normal function and
development of spermatozoa during the fertilization process. This review will focus on the …

Gamete and early embryo development are important stages when genome-scale
epigenetic transitions are orchestrated. The apparent lack of remodeling of differential …

Since the birth of Louise Brown in 1978 via IVF, reproductive specialists have acquired
enormous knowledge and refined several procedures, which are nowadays applied in …

Male infertility is a reproductive disease, and existing clinical solutions for this condition
often involve long and cumbersome sperm sorting methods, including preprocessing and …

Since the birth of Louise Joy Brown, the first baby conceived via in vitro fertilization, more
than 9 million children have been born worldwide using assisted reproductive technologies …

Infertility is a significant problem for human reproduction, with males and females equally
affected. However, the molecular mechanisms underlying male infertility remain unclear …

Infertility is defined as the failure to conceive after at least one year of unprotected
intercourse. Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 …

As with many other diseases, genetic testing in human azoospermia was initially restricted to
karyotype analyses (leading to diagnostic chromosome rearrangement tests for Klinefelter …

This systematic review and meta-analysis summarize the difference in the methylation of the
H19 gene in patients with abnormal versus normal conventional sperm parameters. It also …