TET enzymes are successively expressed during human spermatogenesis and their expression level is pivotal for male fertility
K Ni, T Dansranjavin, N Rogenhofer… - Human …, 2016 - academic.oup.com
STUDY QUESTION Are ten-eleven-translocation (TET) 1–3 family enzymes involved in
human spermatogenesis and do they impact male fertility? SUMMARY ANSWER TET1 …
human spermatogenesis and do they impact male fertility? SUMMARY ANSWER TET1 …
[HTML][HTML] The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis
E Leitão, S Di Persio, S Laurentino, M Wöste… - Clinical …, 2020 - Springer
Background In the past 15 years, numerous studies have described aberrant DNA
methylation of imprinted genes (eg MEST and H19) in sperm of oligozoospermic men, but …
methylation of imprinted genes (eg MEST and H19) in sperm of oligozoospermic men, but …
DNA methylation levels of imprinted and nonimprinted genes DMR s associated with defective human spermatozoa
J Xu, A Zhang, Z Zhang, P Wang, Y Qian, L He… - Andrologia, 2016 - Wiley Online Library
Asthenozoospermia (AS) is a common cause of human male infertility. Recent studies have
shown significant associations of aberrant DNA methylation in spermatozoa with male …
shown significant associations of aberrant DNA methylation in spermatozoa with male …
[HTML][HTML] In Utero Exposure to Metformin Reduces the Fertility of Male Offspring in Adulthood
Metformin is a drug used for the treatment of type 2 diabetes and disorders associated with
insulin resistance. Metformin is also used in the treatment of pregnancy disorders such as …
insulin resistance. Metformin is also used in the treatment of pregnancy disorders such as …
[HTML][HTML] Altered DNA methylation and expression of PLAGL1 in cord blood from assisted reproductive technology pregnancies compared with natural conceptions
RN Vincent, LD Gooding, K Louie, EC Wong, S Ma - Fertility and sterility, 2016 - Elsevier
Objective To investigate DNA methylation and expression of imprinted genes and an
imprinted gene network (IGN) in neonates conceived via assisted reproductive technology …
imprinted gene network (IGN) in neonates conceived via assisted reproductive technology …
[HTML][HTML] Bringing epigenetics into the diagnostics of the andrology laboratory: challenges and perspectives
R Kläver, J Gromoll - Asian journal of andrology, 2014 - journals.lww.com
Recent studies have shown significant associations of aberrant DNA methylation in
spermatozoa with idiopathic male infertility, increased frequency of spontaneous abortions …
spermatozoa with idiopathic male infertility, increased frequency of spontaneous abortions …
Genetic basis of male and female infertility
R Mallepaly, PR Butler, AS Herati… - Genetics of Human …, 2017 - karger.com
Male and female infertility affects close to 50 million couples worldwide according to a recent
World Health Organization estimate. Many of the 25-30% of couples with idiopathic infertility …
World Health Organization estimate. Many of the 25-30% of couples with idiopathic infertility …
Analysis of the global methylation status of human spermatozoa and its association with the tendency of these cells to enter apoptosis
The methylation status of human spermatozoa has been examined in relation to the
isopycnic density of these cells and their tendency to spontaneously default to an apoptotic …
isopycnic density of these cells and their tendency to spontaneously default to an apoptotic …
[HTML][HTML] Semen analysis: update on clinical value, current needs and future perspectives
V Sánchez, J Wistuba, C Mallidis - Reproduction, 2013 - rep.bioscientifica.com
At present, evaluation of male reproductive function consists primarily of routine semen
analysis, a collection of conventional microscopic assessments ideally performed following …
analysis, a collection of conventional microscopic assessments ideally performed following …
Aberrations in sperm DNA methylation patterns are associated with abnormalities in semen parameters of subfertile males
M Laqqan, EF Solomayer, M Hammadeh - Reproductive Biology, 2017 - Elsevier
Infertility affects about 15% of couples worldwide, with approximately 7% of males suffering
from infertility problems. This study was designed to assess the relationship between …
from infertility problems. This study was designed to assess the relationship between …