Sperm epigenetics and male infertility: unraveling the molecular puzzle
M Hosseini, A Khalafiyan, M Zare, H Karimzadeh… - Human Genomics, 2024 - Springer
Background The prevalence of infertility among couples is estimated to range from 8 to 12%.
A paradigm shift has occurred in understanding of infertility, challenging the notion that it …
A paradigm shift has occurred in understanding of infertility, challenging the notion that it …
DNA methylation imprinting errors in spermatogenic cells from maturation arrest azoospermic patients
PI Marques, S Fernandes, F Carvalho, A Barros… - …, 2017 - Wiley Online Library
Imprinting errors have been described in spermatozoa from infertile patients with
oligozoospermia and azoospermia. However, little is known about methylation of imprinted …
oligozoospermia and azoospermia. However, little is known about methylation of imprinted …
What the human sperm methylome tells us
C Camprubí, RA Cigliano, A Salas-Huetos… - …, 2017 - Taylor & Francis
Aim: To characterize the sperm methylome in semen samples from 19 donors with proven
fertility. Materials & methods: Bisulfite-converted sperm DNA was hybridized on the …
fertility. Materials & methods: Bisulfite-converted sperm DNA was hybridized on the …
Evaluation of DNA methylation at imprinted DMRs in the spermatozoa of oligozoospermic men in association with MTHFR C677T genotype
K Louie, A Minor, R Ng, K Poon, V Chow, S Ma - Andrology, 2016 - Wiley Online Library
Altered DNA methylation has been previously identified in the spermatozoa of infertile men;
however, the origins of these errors are poorly understood. DNA methylation is an …
however, the origins of these errors are poorly understood. DNA methylation is an …
[PDF][PDF] Sperm DNA methylation, infertility and transgenerational epigenetics
C Nevin, M Carroll - Journal of Human Genetics & Clinical …, 2015 - researchgate.net
The role of the epigenome in the regulation of gene expression is well known. DNA
methylation in sperm has gained increasing interest with the finding that aberrant …
methylation in sperm has gained increasing interest with the finding that aberrant …
Altered crossover distribution and frequency in spermatocytes of infertile men with azoospermia
H Ren, K Ferguson, G Kirkpatrick, T Vinning, V Chow… - PloS one, 2016 - journals.plos.org
During meiosis, homologous chromosomes pair to facilitate the exchange of DNA at
crossover sites along the chromosomes. The frequency and distribution of crossover …
crossover sites along the chromosomes. The frequency and distribution of crossover …
Epigenetics of nonobstructive azoospermia
Nonobstructive azoospermia (NOA) is a severe and heterogeneous form of male factor
infertility caused by dysfunction of spermatogenesis. Although various factors are well …
infertility caused by dysfunction of spermatogenesis. Although various factors are well …
Effects of different extenders on epigenetic patterns and functional parameters of bull sperm during cryopreservation process
R Fouladvandi, AA Masoudi, M Totonchi… - … in Domestic Animals, 2024 - Wiley Online Library
The cryopreservation process induces alterations in cellular parameters and epigenetic
patterns in bull sperm, which can be prevented by adding cryoprotectants in the freezing …
patterns in bull sperm, which can be prevented by adding cryoprotectants in the freezing …
Expression and localization of vascular endothelial growth factor and its receptors in pig corpora lutea during the oestrous cycle
U Boonyaprakob, JE Gadsby, V Hedgpeth… - …, 2003 - rep.bioscientifica.com
Expression and localization of mRNAs for vascular endothelial growth factor (VEGF), VEGF
receptor 1 (Flt) and VEGF receptor 2 (KDR)(VEGFR-1 and VEGFR-2, respectively) were …
receptor 1 (Flt) and VEGF receptor 2 (KDR)(VEGFR-1 and VEGFR-2, respectively) were …
Lack of association of MTHFR rs1801133 polymorphism and CTCFL mutations with sperm methylation errors in infertile patients
C Camprubí, M Pladevall, M Grossmann… - Journal of assisted …, 2013 - Springer
Purpose To find out whether the MTHFR rs1801133 polymorphism is a risk factor for male
infertility in the Spanish population. To determine if a pattern of sperm DNA hypomethylation …
infertility in the Spanish population. To determine if a pattern of sperm DNA hypomethylation …