Background The prevalence of infertility among couples is estimated to range from 8 to 12%.
A paradigm shift has occurred in understanding of infertility, challenging the notion that it …

Imprinting errors have been described in spermatozoa from infertile patients with
oligozoospermia and azoospermia. However, little is known about methylation of imprinted …

Aim: To characterize the sperm methylome in semen samples from 19 donors with proven
fertility. Materials & methods: Bisulfite-converted sperm DNA was hybridized on the …

Altered DNA methylation has been previously identified in the spermatozoa of infertile men;
however, the origins of these errors are poorly understood. DNA methylation is an …

The role of the epigenome in the regulation of gene expression is well known. DNA
methylation in sperm has gained increasing interest with the finding that aberrant …

During meiosis, homologous chromosomes pair to facilitate the exchange of DNA at
crossover sites along the chromosomes. The frequency and distribution of crossover …

Nonobstructive azoospermia (NOA) is a severe and heterogeneous form of male factor
infertility caused by dysfunction of spermatogenesis. Although various factors are well …

The cryopreservation process induces alterations in cellular parameters and epigenetic
patterns in bull sperm, which can be prevented by adding cryoprotectants in the freezing …

Expression and localization of mRNAs for vascular endothelial growth factor (VEGF), VEGF
receptor 1 (Flt) and VEGF receptor 2 (KDR)(VEGFR-1 and VEGFR-2, respectively) were …

Purpose To find out whether the MTHFR rs1801133 polymorphism is a risk factor for male
infertility in the Spanish population. To determine if a pattern of sperm DNA hypomethylation …