The cerebral effects of ascent to high altitudes

MH Wilson, S Newman, CH Imray - The Lancet Neurology, 2009 - thelancet.com
Cellular hypoxia is the common final pathway of brain injury that occurs not just after
asphyxia, but also when cerebral perfusion is impaired directly (eg, embolic stroke) or …

High-altitude cerebral edema: its own entity or end-stage acute mountain sickness?

REF Turner, H Gatterer, M Falla… - Journal of Applied …, 2021 - journals.physiology.org
High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

[图书][B] High altitude medicine and physiology 5E

J West, R Schoene, A Luks, J Milledge - 2012 - books.google.com
A comprehensive update to this preeminent and accessible text, this fifth edition of a
bestseller was developed as a response to man's attempts to climb unaided to higher …

[HTML][HTML] Emerging concepts in acute mountain sickness and high-altitude cerebral edema: from the molecular to the morphological

DM Bailey, P Bärtsch, M Knauth… - Cellular and Molecular …, 2009 - Springer
Acute mountain sickness (AMS) is a neurological disorder that typically affects mountaineers
who ascend to high altitude. The symptoms have traditionally been ascribed to intracranial …

[HTML][HTML] Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness

DE Leaf, DS Goldfarb - Journal of applied physiology, 2007 - journals.physiology.org
Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is the most commonly used and
best-studied agent for the amelioration of acute mountain sickness (AMS). The actual …

[图书][B] High altitude medicine and physiology

JB West, RB Schoene, JS Milledge, MP Ward - 2007 - api.taylorfrancis.com
1 History 1 2 The atmosphere 16 3 Geography and the human response to altitude 28 4
Genetics and high altitude 40 5 Altitude acclimatization and deterioration 53 6 Control of …

Magnetic resonance imaging evidence of cytotoxic cerebral edema in acute mountain sickness

K Kallenberg, DM Bailey, S Christ… - Journal of Cerebral …, 2007 - journals.sagepub.com
The present study applied T2-and diffusion-weighted magnetic resonance imaging to
examine if mild cerebral edema and subsequent brain swelling are implicated in the …

Acute mountain sickness: controversies and advances

P Bartsch, DM Bailey, MM Berger, M Knauth… - … altitude medicine & …, 2004 - liebertpub.com
This review discusses the impact of recent publications on pathophysiologic concepts and
on practical aspects of acute mountain sickness (AMS). Magnetic resonance imaging …

Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs

VHN Estrada, DM Franco, RD Medina… - Cochrane Database …, 2017 - cochranelibrary.com
Background High altitude illness (HAI) is a term used to describe a group of cerebral and
pulmonary syndromes that can occur during travel to elevations above 2500 metres (8200 …

Free radical-mediated damage to barrier function is not associated with altered brain morphology in high-altitude headache

DM Bailey, R Roukens, M Knauth… - Journal of Cerebral …, 2006 - journals.sagepub.com
The present study combined molecular and neuroimaging techniques to examine if free
radical-mediated damage to barrier function in hypoxia would result in extracellular edema …