Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Various biological attributes associated with individual fitness in animals change predictably
over the lifespan of an organism. Therefore, the study of animal ecology and the work of …

Naked mole rats (NMRs) live an exceptionally long life, appear not to exhibit age-related
decline in physiological capacity and are resistant to age-related diseases. However, it has …

Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …

Epigenetic approaches for estimating the age of living organisms are revolutionizing studies
of long‐lived species. Molecular biomarkers that allow age estimates from small tissue …

Social nonhuman animals are powerful models for studying underlying factors related to
lifelong health outcomes following early life adversities (ELAs). ELAs can be linked to …

Methylation levels at specific CpG positions in the genome have been used to develop
accurate estimators of chronological age in humans, mice, and other species. Although …

Human DNA methylation data have previously been used to develop highly accurate
biomarkers of aging (“epigenetic clocks”). Subsequent studies demonstrate that similar …

In humans, social participation and integration wane with advanced age, a pattern
hypothesized to stem from cognitive or physical decrements. Similar age-related decreases …

Geographically isolated populations, specifically island‐mainland counterparts, tend to
exhibit phenotypic variation in many species. The so‐called island syndrome occurs when …