Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …
been extensively researched since the landmark report by Morpurgo (1897) of “work …
The effect of healthy lifestyle strategies on the management of insulin resistance in children and adolescents with obesity: a narrative review
V Calcaterra, E Verduci, M Vandoni, V Rossi, G Fiore… - Nutrients, 2022 - mdpi.com
Childhood obesity is characterized by an increased risk of several metabolic derangements
including insulin resistance (IR). The strongest recommendations to prevent obesity and …
including insulin resistance (IR). The strongest recommendations to prevent obesity and …
Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men
We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA
responses to one bout of lower load (LL) versus higher load (HL) resistance exercise …
responses to one bout of lower load (LL) versus higher load (HL) resistance exercise …
DNA methylation as a mediator of genetic and environmental influences on Parkinson's disease susceptibility: Impacts of alpha-Synuclein, physical activity, and …
SL Schaffner, MS Kobor - Frontiers in genetics, 2022 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder with a complex etiology and
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …
Molecular mechanisms underlying pluripotency and self-renewal of embryonic stem cells
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …
Multiple myeloma: challenges encountered and future options for better treatment
Multiple myeloma (MM) is a malignant hematological disease. The disease is characterized
by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for …
by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for …
Molecular adaptations in response to exercise training are associated with tissue-specific transcriptomic and epigenomic signatures
Regular exercise has many physical and brain health benefits, yet the molecular
mechanisms mediating exercise effects across tissues remain poorly understood. Here we …
mechanisms mediating exercise effects across tissues remain poorly understood. Here we …
Epigenomic links between social determinants of health and symptoms: a scoping review
M Ray, MKK Wallace, SC Grayson… - Biological Research …, 2023 - journals.sagepub.com
Social determinants of health (SDoH) impact health and wellness. The link between SDoH
and adverse health outcomes, including symptom occurrence and severity, may be …
and adverse health outcomes, including symptom occurrence and severity, may be …
The Notch1/Hes1 signaling pathway affects autophagy by adjusting DNA methyltransferases expression in a valproic acid-induced autism spectrum disorder model
Y Li, L Ma, Y Deng, Z Du, B Guo, J Yue, X Liu… - …, 2023 - Elsevier
As a pervasive neurodevelopmental disease, autism spectrum disorder (ASD) is caused by
both hereditary and environmental elements. Research has demonstrated the functions of …
both hereditary and environmental elements. Research has demonstrated the functions of …
Genome-wide epigenetic modifications in sports horses during training as an adaptation phenomenon
With his bicentennial breeding history based on athletic performance, the Thoroughbred
horse can be considered the equine sport breed. Although genomic and transcriptomic tools …
horse can be considered the equine sport breed. Although genomic and transcriptomic tools …