The presence of CpGs in AAV gene therapy vectors induces a plasmacytoid dendritic cell-like population very early after administration

JD Glenn, H Negash, W Henry, R Qian, Y Liu… - Cellular …, 2024 - Elsevier
AAV-mediated gene transfer is a promising platform still plagued by potential host-derived,
antagonistic immune responses to therapeutic components. CpG-mediated TLR9 …

The presence of CpGs in AAV gene therapy vectors induces a plasmacytoid dendritic cell-like population very early after administration.

JD Glenn, H Negash, W Henry, R Qian, Y Liu… - Cellular …, 2024 - europepmc.org
AAV-mediated gene transfer is a promising platform still plagued by potential host-derived,
antagonistic immune responses to therapeutic components. CpG-mediated TLR9 …

The presence of CpGs in AAV gene therapy vectors induces a plasmacytoid dendritic cell-like population very early after administration

JD Glenn, H Negash, W Henry, R Qian, Y Liu… - Cellular … - pubmed.ncbi.nlm.nih.gov
AAV-mediated gene transfer is a promising platform still plagued by potential host-derived,
antagonistic immune responses to therapeutic components. CpG-mediated TLR9 …