Chromosomal regions can adopt stable and heritable alternative states resulting in bistable
gene expression without changes to the DNA sequence. Such epigenetic control is often …

The histone tails on the nucleosome surface are subject to enzyme-catalyzed modifications
that may, singly or in combination, form a code specifying patterns of gene expression …

Assembly, mobilization and disassembly of nucleosomes can influence the regulation of
gene expression and other processes that act on eukaryotic DNA. Distinct nucleosome …

The detailed positions of nucleosomes profoundly impact gene regulation and are partly
encoded by the genomic DNA sequence. However, less is known about the functional …

Arrays of regularly spaced nucleosomes dominate chromatin and are often phased by
alignment to reference sites like active promoters. How the distances between nucleosomes …

ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in
eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA …

The plasticity of chromatin organization as chromosomes undergo a full compendium of
transactions including DNA replication, recombination, chromatin compaction, and changes …

Nucleosomes are the fundamental structural unit of chromatin. In addition to stabilizing the
DNA polymer, nucleosomes are modified in ways that reflect and affect gene expression in …

The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic
structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of …

Epigenetic cell memory allows distinct gene expression patterns to persist in different cell
types despite a common genotype. Although different patterns can be maintained by the …