A growing body of evidence indicates a crucial role of miRNA regulatory function in a variety
of mechanisms that contribute to the development of diseases. In our previous work …

Chronic venous disease (CVD) is a vascular disease of lower limbs with high prevalence
worldwide. Pathologic features include varicose veins, venous valves dysfunction and skin …

Lower extremity artery disease (LEAD) is an underdiagnosed and globally underestimated
vascular disease caused by the progressive and chronic formation of atherosclerotic …

Atherosclerosis and its comorbidities are the major contributors to the global burden of death
worldwide. Lower extremities arterial disease (LEAD) is a common manifestation of …

Further determination of miRNA regulatory circuits and defining miRNAs-specific target
genes remains key to future miRNA-based therapeutic applications toward vascular disease …

Cardio vascular disease (CVD) has raised morbidity and mortality rate in near future and
also remains a major financial burden in most developed countries around the world …

Peripheral artery disease (PAD) is a marker disease for generalized atherosclerosis and
represents one of the world's major causes of morbidity and mortality. Many studies have …

Most current circulating miRNA biomarkers are derived from peripheral venous blood,
whereas miRNA deregulation in arterial blood in disease conditions has been largely …

Peripheral artery disease (PAD) is a disease of atherosclerosis in the lower extremities. PAD
carries a massive burden worldwide, while diagnosis and treatment options are often …

Objective: Atherosclerosis is the underlying cause of most cardiovascular diseases. The
main cell types associated with disease progression in the vascular wall are endothelial …