Transcription regulation of E‐cadherin by zinc finger E‐box binding homeobox proteins in solid tumors

TS Wong, W Gao, JYW Chan - BioMed research international, 2014 - Wiley Online Library
Downregulation of E‐cadherin in solid tumors with regional migration and systematic
metastasis is well recognized. In view of its significance in tumorigenesis and solid cancer …

ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease

M Singh, NS Spoelstra, A Jean, E Howe, KC Torkko… - Modern …, 2008 - nature.com
Zinc-finger E-box-binding homeobox 1 (ZEB1) is a transcription factor containing two
clusters of Kruppel-type zinc-fingers, by which it binds E-box-like sequences on target DNAs …

Clinicopathological significance of ZEB-1 and E-cadherin proteins in patients with oral cavity squamous cell carcinoma

X Yao, S Sun, X Zhou, Q Zhang, W Guo… - OncoTargets and …, 2017 - Taylor & Francis
Background Zinc-finger E-box binding homeobox 1 (ZEB-1), a member of the ZFH family,
plays a key role in epithelial–mesenchymal transition during tumor progression in various …

Involvement of ZEB1 and E-cadherin in the invasion of lung squamous cell carcinoma

J Zhang, C Lu, J Zhang, J Kang, C Cao, M Li - Molecular biology reports, 2013 - Springer
This study intended to investigate the expression of the ZEB1 and E-cadherin proteins in
lung squamous cell carcinoma (LSCC) tissues and to examine the clinicopathological …

[HTML][HTML] ZEB1 promotes invasion and metastasis of endometrial cancer by interacting with HDGF and inducing its transcription

YY Xiao, L Lin, YH Li, HP Jiang, LT Zhu… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Zinc finger E-box binding homeobox 1 (ZEB1), as a typical transcription inhibitory factor of E-
cadherin, plays a major role in stimulating the invasion and metastasis of tumors via …

The crucial role of ZEB2: from development to epithelial‐to‐mesenchymal transition and cancer complexity

M Fardi, M Alivand, B Baradaran… - Journal of cellular …, 2019 - Wiley Online Library
Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which
is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT is a conserved …

Immunohistochemical analysis of the expression of E‐cadherin and ZEB1 in non‐small cell lung cancer

D Matsubara, Y Kishaba, T Yoshimoto… - Pathology …, 2014 - Wiley Online Library
We performed an immunohistochemical analysis of the expression of zinc‐finger E‐box
binding homeobox 1 (ZEB1), a master regulator of epithelial‐mesenchymal transition (EMT) …

Regulation of ZEB1 function and molecular associations in tumor progression and metastasis

M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …

The role of the ZEB family of transcription factors in development and disease

C Vandewalle, F Van Roy, G Berx - Cellular and molecular life sciences, 2009 - Springer
The ZEB family of zinc finger transcription factors are essential players during normal
embryonic development. One characteristic is that they induce epithelial to mesenchymal …

Effect of downregulation of ZEB1 on vimentin expression, tumour migration and tumourigenicity of melanoma B16F10 cells and CSCs

J Dou, X He, Y Liu, Y Wang, F Zhao… - Cell biology …, 2014 - Wiley Online Library
Zinc‐finger E‐box binding homeobox 1 (ZEB1) is a master regulator of epithelial‐
mesenchymal transition (EMT) and has been implicated in primary epithelial cancer …