Exosomes from mesenchymal stem cells overexpressing MIF enhance myocardial repair

X Liu, X Li, W Zhu, Y Zhang, Y Hong… - Journal of cellular …, 2020 - Wiley Online Library
Accumulating evidence has shown that mesenchymal stem cell (MSC)‐derived exosomes
(exo) mediate cardiac repair following myocardial infarction (MI). Macrophage migration …

[HTML][HTML] Macrophage migration inhibitory factor facilitates the therapeutic efficacy of mesenchymal stem cells derived exosomes in acute myocardial infarction through …

W Zhu, L Sun, P Zhao, Y Liu, J Zhang, Y Zhang… - Journal of …, 2021 - Springer
Background Exosome transplantation is a promising cell-free therapeutic approach for the
treatment of ischemic heart disease. The purpose of this study was to explore whether …

Mesenchymal stromal cell-derived exosomes attenuate myocardial ischaemia-reperfusion injury through miR-182-regulated macrophage polarization

J Zhao, X Li, J Hu, F Chen, S Qiao, X Sun… - Cardiovascular …, 2019 - academic.oup.com
Abstract Aims Mesenchymal stromal cells (MSCs) gradually become attractive candidates
for cardiac inflammation modulation, yet understanding of the mechanism remains elusive …

Transplantation of cardiac mesenchymal stem cell-derived exosomes promotes repair in ischemic myocardium

C Ju, Y Shen, G Ma, Y Liu, J Cai, I Kim… - Journal of …, 2018 - Springer
Our previous study demonstrated the beneficial effects of exosomes secreted by cardiac
mesenchymal stem cells (C-MSC-Exo) in protecting acute ischemic myocardium from …

[HTML][HTML] MiRNA-sequence indicates that mesenchymal stem cells and exosomes have similar mechanism to enhance cardiac repair

L Shao, Y Zhang, B Lan, J Wang, Z Zhang… - BioMed research …, 2017 - hindawi.com
Mesenchymal stem cells (MSCs) repair infarcted heart through paracrine mechanism. We
sought to compare the effectiveness of MSCs and MSC-derived exosomes (MSC-Exo) in …

[HTML][HTML] Exosomes derived from mesenchymal stem cells rescue myocardial ischaemia/reperfusion injury by inducing cardiomyocyte autophagy via AMPK and Akt …

L Liu, X Jin, CF Hu, R Li, Z Zhou… - Cellular physiology and …, 2017 - karger.com
Background/Aims: Reperfusion after an ischaemic insult might cause infarct extension.
Mesenchymal stem cell (MSC)-derived exosomes could attenuate myocardial remodelling in …

[HTML][HTML] Bone marrow mesenchymal stem cell‑derived exosomes protect against myocardial infarction by promoting autophagy

L Zou, X Ma, S Lin, B Wu… - Experimental and …, 2019 - spandidos-publications.com
Exosomes have been demonstrated to be effective in the treatment of a variety of cardiac
disorders. However, the effects of mesenchymal stem cell (MSC) exosomes on myocardial …

[HTML][HTML] Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence

H Zheng, X Liang, Q Han, Z Shao, Y Zhang… - Journal of …, 2021 - Springer
Background Application of mesenchymal stem cell-derived exosomes (MSC-EXO) has
emerged as a novel therapeutic strategy for myocardial infarction (MI). Our previous study …

Exosomes derived from SDF1‐overexpressing mesenchymal stem cells inhibit ischemic myocardial cell apoptosis and promote cardiac endothelial microvascular …

XH Gong, H Liu, SJ Wang, SW Liang… - Journal of cellular …, 2019 - Wiley Online Library
Exosomes extracted from mesenchymal stem cells (MSCs) was reported to reduce
myocardial ischemia/reperfusion damage. Besides, stromal‐derived factor 1 (SDF1a) …

Exosomal miR-301 derived from mesenchymal stem cells protects myocardial infarction by inhibiting myocardial autophagy

Y Li, R Yang, B Guo, H Zhang, H Zhang, S Liu… - … and biophysical research …, 2019 - Elsevier
Purpose To investigate the protective effects of miR-301 in exosomes secreted by bone
mesenchymal stem cells (BMSCs) on rats' myocardial infarction (MI). Methods After isolation …